Structure of PDB 4fmn Chain B Binding Site BS02

Receptor Information
>4fmn Chain B (length=213) Species: 559292 (Saccharomyces cerevisiae S288C) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
ELEDFEQGEKYLTLTVSKNDFKKMEVVGQFNLGFIIVTRKVDNKYDLFIV
DQHASDEKYNFETLQAVTVFKSQKLIIPQPVELSELVVLDNLPVFEKNGF
KLKISRVKLLSLPTSKQTLFDLGDFNELIHLIKEDGGLRRDNIRCSKIRS
MFAMRACRSSIMIGKPLNKKTMTRVVHNLSELDKPWNCPHGRPTMRHLME
LRDWSSFSKDYEI
Ligand information
Ligand IDZN
InChIInChI=1S/Zn/q+2
InChIKeyPTFCDOFLOPIGGS-UHFFFAOYSA-N
SMILES
SoftwareSMILES
CACTVS 3.341[Zn++]
ACDLabs 10.04
OpenEye OEToolkits 1.5.0		[Zn+2]
FormulaZn
NameZINC ION
ChEMBLCHEMBL1236970
DrugBankDB14532
ZINC
PDB chain4fmn Chain B Residue 902 [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
Receptor-Ligand Complex Structure
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PDB4fmn Structure of the MutL alpha C-terminal domain reveals how Mlh1 contributes to Pms1 endonuclease site.
Resolution2.69 Å
Binding residue
(original residue number in PDB)		E707 C848 H850
Binding residue
(residue number reindexed from 1)		E57 C188 H190
Annotation score1
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Molecular Function
GO:0005524 ATP binding
GO:0016887 ATP hydrolysis activity
GO:0140664 ATP-dependent DNA damage sensor activity
Biological Process
GO:0006298 mismatch repair
Cellular Component
GO:0032300 mismatch repair complex

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Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:4fmn, PDBe:4fmn, PDBj:4fmn
PDBsum4fmn
PubMed23435383
UniProtP14242|PMS1_YEAST DNA mismatch repair protein PMS1 (Gene Name=PMS1)

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