Structure of PDB 4esj Chain B Binding Site BS02

Receptor Information
>4esj Chain B (length=241) Species: 170187 (Streptococcus pneumoniae TIGR4) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
MELHFNLELVETYKSNSQKARILTEDWVYRQSYCPNCGNNPLNHFEVADF
YCNHCSEEFELKSKKGNFSSTINDGAYATMMKRVQADNNPNFFFLTYTKN
FEVNNFLVLPKQFVTPKSIIQRKPWIGCNIDLSQVPSKGRIFLVQDGQVR
DPEKVTKEFKQGLFLRKSSLSSRGWTIEILNCIDKIEGSEFTLEDMYRFE
SDLKNIFVKNNHIKEKIRQQLQILRDKEIIEFKGRGKYRKL
Ligand information
Receptor-Ligand Complex Structure
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PDB4esj Crystal structure and mechanism of action of the N6-methyladenine-dependent type IIM restriction endonuclease R.DpnI.
Resolution2.05 Å
Binding residue
(original residue number in PDB)
L206 R231 Q232 Q235 R238 F245 G249 Y251
Binding residue
(residue number reindexed from 1)
L193 R218 Q219 Q222 R225 F232 G236 Y238
Enzymatic activity
Enzyme Commision number 3.1.21.4: type II site-specific deoxyribonuclease.
Gene Ontology
Molecular Function
GO:0004519 endonuclease activity
GO:0009036 type II site-specific deoxyribonuclease activity
Biological Process
GO:0009307 DNA restriction-modification system

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Molecular Function

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Biological Process
External links
PDB RCSB:4esj, PDBe:4esj, PDBj:4esj
PDBsum4esj
PubMed22610857
UniProtP0A460|T2D1_STRR6 Type II Methyl-directed restriction enzyme DpnI (Gene Name=dpnC)

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