Structure of PDB 4cs0 Chain B Binding Site BS02

Receptor Information
>4cs0 Chain B (length=127) Species: 83333 (Escherichia coli K-12) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
MKLTIIRLEKFSDQDRIDLQKIWPEYSPSSLQVDDNHRIYAARFNERLLA
AVRVTLSGTEGALDSLRVREVTRRRGVGQYLLEEVLRNNPGVSCWWMADA
GVEDRGVMTAFMQALGFTAQQGGWEKC
Ligand information
Ligand IDMG
InChIInChI=1S/Mg/q+2
InChIKeyJLVVSXFLKOJNIY-UHFFFAOYSA-N
SMILES
SoftwareSMILES
ACDLabs 10.04
OpenEye OEToolkits 1.5.0		[Mg+2]
CACTVS 3.341[Mg++]
FormulaMg
NameMAGNESIUM ION
ChEMBL
DrugBankDB01378
ZINC
PDB chain4cs0 Chain B Residue 1129 [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
Receptor-Ligand Complex Structure
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PDB4cs0 The Structure of the Pand/Panz Protein Complex Reveals Negative Feedback Regulation of Pantothenate Biosynthesis by Coenzyme A.
Resolution2.1 Å
Binding residue
(original residue number in PDB)		T72 R73 R74 R75 V77
Binding residue
(residue number reindexed from 1)		T72 R73 R74 R75 V77
Annotation score4
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Molecular Function
GO:0005515 protein binding
GO:0016747 acyltransferase activity, transferring groups other than amino-acyl groups
GO:1905502 acetyl-CoA binding
Biological Process
GO:0015940 pantothenate biosynthetic process
GO:0016485 protein processing
GO:0031638 zymogen activation

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Molecular Function
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Biological Process
External links
PDB RCSB:4cs0, PDBe:4cs0, PDBj:4cs0
PDBsum4cs0
PubMed25910242
UniProtP37613|PANZ_ECOLI PanD regulatory factor (Gene Name=panZ)

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