Structure of PDB 4awz Chain B Binding Site BS02

Receptor Information

>4awz Chain B (length=267) Species: 287 (Pseudomonas aeruginosa) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]

RGCADDAGWNDPAMPLKVYGNTWYVGTCGISALLVTSDAGHILVDAATPQ
AGPQILANIRALGFRPEDVRAIVFSHEHFDHAGSLAELQKATGAPVYARA
PAIDTLKRGLPDRTDPQFEVAEPVAPVANIVTLADDGVVSVGPLALTAVA
SPGHTPGGTSWTWRSCEGDDCRQMVYADSLTAISDDVFRYSDDAAHPGYL
AAFRNTLARVAALDCDILVTPHPSASGLWNRIGPRAAAPLMDTTACRRYA
QGARQRLEKRLAEEAAT

Ligand information

Ligand ID

InChI

InChI=1S/Zn/q+2

InChIKey

PTFCDOFLOPIGGS-UHFFFAOYSA-N

SMILES

Software	SMILES
CACTVS 3.341	[Zn++]
ACDLabs 10.04 OpenEye OEToolkits 1.5.0	[Zn+2]

Formula

Name

ZINC ION

PDB chain

4awz Chain B Residue 3230 [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]

Receptor-Ligand Complex Structure

Global view

Local view

Structure summary

[Spin on] [Spin off] [Reset]
[High quality] [Low quality]
[White background] [Black background]

PDB	4awz Crystal Structure of the Mobile Metallo-Beta-Lactamase Aim-1 from Pseudomonas Aeruginosa: Insights Into Antibiotic Binding and the Role of Gln157.
Resolution	1.8 Å
Binding residue (original residue number in PDB)	H116 H118 H196
Binding residue (residue number reindexed from 1)	H76 H78 H154
Annotation score	4

Enzymatic activity

Catalytic site (original residue number in PDB)	H116 H118 D120 H121 H196 F228 H263
Catalytic site (residue number reindexed from 1)	H76 H78 D80 H81 H154 F188 H222
Enzyme Commision number	?

External links

PDB	RCSB:4awz, PDBe:4awz, PDBj:4awz
PDBsum	4awz
PubMed	22664968
UniProt	B5DCA0

[Back to BioLiP]