Structure of PDB 4a0a Chain B Binding Site BS02

Receptor Information
>4a0a Chain B (length=355) Species: 7955 (Danio rerio) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
GQTSILHYIYKSSLGQSIHAQLRQCLQEPFIRSLKSYKLHRTASPFDRRV
TSLEWHPTHPTTVAVGSKGGDIILWDYDVQNKTSFIQGMGPGDAITGMKF
NQFNTNQLFVSSIRGATTLRDFSGSVIQVFAKTDSWDYWYCCVDVSVSRQ
MLATGDSTGRLLLLGLDGHEIFKEKLHKAKVTHAEFNPRCDWLMATSSVD
ATVKLWDLRNIKDKNSYIAEMPHEKPVNAAYFNPTDSTKLLTTDQRNEIR
VYSSYDWSKPDQIIIHPHRQFQHLTPIKATWHPMYDLIVAGRYPDDQLLL
NDKRTIDIYDANSGGLVHQLRDPNAAGIISLNKFSPTGDVLASGMGFNIL
IWNRE
Ligand information
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

[Spin on] [Spin off] [Reset]
[High quality] [Low quality]
[White background] [Black background]
[Spin on] [Spin off] [Reset]
[High quality] [Low quality]
[White background] [Black background]
PDB4a0a The Molecular Basis of Crl4(Ddb2/Csa) Ubiquitin Ligase Architecture, Targeting, and Activation
Resolution3.6 Å
Binding residue
(original residue number in PDB)		R369 F371 Q372 H373 Y393 I428 F447
Binding residue
(residue number reindexed from 1)		R269 F271 Q272 H273 Y293 I328 F347
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Molecular Function
GO:0003684 damaged DNA binding
Biological Process
GO:0006281 DNA repair
Cellular Component
GO:0005634 nucleus
GO:0080008 Cul4-RING E3 ubiquitin ligase complex

View graph for
Molecular Function
View graph for
Biological Process
View graph for
Cellular Component
External links
PDB RCSB:4a0a, PDBe:4a0a, PDBj:4a0a
PDBsum4a0a
PubMed22118460
UniProtQ2YDS1|DDB2_DANRE DNA damage-binding protein 2 (Gene Name=ddb2)

[Back to BioLiP]