Structure of PDB 3zx5 Chain B Binding Site BS02

Receptor Information

>3zx5 Chain B (length=251) Species: 262724 (Thermus thermophilus HB27)

MIVFTDLDGTLLDERGELGPAREALERLRALGVPVVPVTAKTRKEVEALG
LEPPFIVENGGGLYLPRDWPVRAGRPKGGYRVVSLAWPYRKVRARLREAE
ALAGRPILGYGDLTAEAVARLTGLSREAARRAKAREYDETLVLCPEEVEA
VLEALEAVGLEWTHGGRFYHAAKGADKGRAVARLRALWPDPEEARFAVGL
GDSLNDLPLFRAVDLAVYVGRGDPPEGVLATPAPGPEGFRYAVERYLLPR
L

Ligand information

• Ligand ID: VN4
• InChI: InChI=1S/3O.V/q;;-1;
• InChIKey: ALTWGIIQPLQAAM-UHFFFAOYSA-N
• SMILES:
  ACDLabs 10.04
  CACTVS 3.341
  OpenEye OEToolkits 1.5.0: [O-][V](=O)=O
• Formula: O3 V
• Name: oxido(dioxo)vanadium
• PDB chain: 3zx5 Chain B Residue 261

Receptor-Ligand Complex Structure

Structure summary

• PDB: 3zx5 The Three-Dimensional Structure of Mannosyl-3-Phosphoglycerate Phosphatase from Thermus Thermophilus Hb27: A New Member of the Haloalkanoic Acid Dehalogenase Superfamily.
• Resolution: 1.81 Å
• Binding residue (original residue number in PDB): D6 L7 D8 T39 A40 K177
• Binding residue (residue number reindexed from 1): D6 L7 D8 T39 A40 K177
• Annotation score: 1

Enzymatic activity

• Enzyme Commision number: 3.1.3.70: mannosyl-3-phosphoglycerate phosphatase.

Gene Ontology

Molecular Function

• GO:0000287 magnesium ion binding
• GO:0016791 phosphatase activity
• GO:0046872 metal ion binding
• GO:0050531 mannosyl-3-phosphoglycerate phosphatase activity

Biological Process

• GO:0051479 mannosylglycerate biosynthetic process

Cellular Component

• GO:0005737 cytoplasm
• GO:0005829 cytosol

External links

• PDB: RCSB:3zx5, PDBe:3zx5, PDBj:3zx5
• PDBsum: 3zx5
• PubMed: 21961705
• UniProt: Q72K29