Structure of PDB 3wuc Chain B Binding Site BS02

Receptor Information
>3wuc Chain B (length=137) Species: 8355 (Xenopus laevis) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
GSMDMEPDVRITNLNLHKGHRVEVRGRIAKGTNRFAVDLGTDSRNLICHC
NPRFEYSVDKNTIVLNSKQNDVWDIEKKETAFPFKSGSETMLIFDFEDCI
TVHLPDGKEIPFTCRFPIEVINYLALNNIELISISVH
Ligand information
Ligand IDGAL
InChIInChI=1S/C6H12O6/c7-1-2-3(8)4(9)5(10)6(11)12-2/h2-11H,1H2/t2-,3+,4+,5-,6-/m1/s1
InChIKeyWQZGKKKJIJFFOK-FPRJBGLDSA-N
SMILES
SoftwareSMILES
CACTVS 3.370OC[C@H]1O[C@@H](O)[C@H](O)[C@@H](O)[C@H]1O
OpenEye OEToolkits 1.7.2C(C1C(C(C(C(O1)O)O)O)O)O
CACTVS 3.370OC[CH]1O[CH](O)[CH](O)[CH](O)[CH]1O
ACDLabs 12.01OC1C(O)C(OC(O)C1O)CO
OpenEye OEToolkits 1.7.2C([C@@H]1[C@@H]([C@@H]([C@H]([C@@H](O1)O)O)O)O)O
FormulaC6 H12 O6
Namebeta-D-galactopyranose;
beta-D-galactose;
D-galactose;
galactose
ChEMBLCHEMBL300520
DrugBank
ZINCZINC000002597049
PDB chain3wuc Chain D Residue 2 [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

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PDB3wuc Crystal structure of a Xenopus laevis skin proto-type galectin, close to but distinct from galectin-1.
Resolution1.6 Å
Binding residue
(original residue number in PDB)		R32 H47 R51 W71 E74
Binding residue
(residue number reindexed from 1)		R34 H49 R53 W73 E76
Annotation score4
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Molecular Function
GO:0030246 carbohydrate binding
GO:0043236 laminin binding
Cellular Component
GO:0005615 extracellular space
GO:0062023 collagen-containing extracellular matrix

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Molecular Function
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Cellular Component
External links
PDB RCSB:3wuc, PDBe:3wuc, PDBj:3wuc
PDBsum3wuc
PubMed25804418
UniProtQ91786

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