Structure of PDB 3wtg Chain B Binding Site BS02

Receptor Information

>3wtg Chain B (length=146) Species: 8790 (Dromaius novaehollandiae)

VQWSAEEKQLISSLWGKVNVAECGAEALARLLIVYPWTQRFFTSFGNLSS
ASAIIGNPMVRAHGKKVLTSFGDAVKNLDNIKNTFAQLSELHCDKLHVDP
ENFRLLGDILIIVLAAHFAKEFTPECQAAWQKLVRVVAHALARKYH

Ligand information

• Ligand ID: OXY
• InChI: InChI=1S/O2/c1-2
• InChIKey: MYMOFIZGZYHOMD-UHFFFAOYSA-N
• SMILES:
  CACTVS 3.341
  OpenEye OEToolkits 1.5.0: O=O
• Formula: O2
• Name: OXYGEN MOLECULE
• ChEMBL: CHEMBL1234886
• DrugBank: DB09140
• PDB chain: 3wtg Chain B Residue 202

Receptor-Ligand Complex Structure

Structure summary

• PDB: 3wtg Purification and preliminary structural studies of hemoglobin from high oxygen affinity species Emu (Dromaius novaehollandiae) at neutral pH
• Resolution: 2.3 Å
• Binding residue (original residue number in PDB): H63 V67
• Binding residue (residue number reindexed from 1): H63 V67
• Annotation score: 4

Gene Ontology

Molecular Function

• GO:0004601 peroxidase activity
• GO:0005344 oxygen carrier activity
• GO:0019825 oxygen binding
• GO:0020037 heme binding
• GO:0031720 haptoglobin binding
• GO:0043177 organic acid binding
• GO:0046872 metal ion binding

Biological Process

• GO:0015671 oxygen transport
• GO:0042744 hydrogen peroxide catabolic process
• GO:0098869 cellular oxidant detoxification

Cellular Component

• GO:0005833 hemoglobin complex
• GO:0031838 haptoglobin-hemoglobin complex
• GO:0072562 blood microparticle

External links

• PDB: RCSB:3wtg, PDBe:3wtg, PDBj:3wtg
• PDBsum: 3wtg
• UniProt: A0A075B5G0