Structure of PDB 3uyk Chain B Binding Site BS02

Receptor Information
>3uyk Chain B (length=369) Species: 60894 (Saccharopolyspora spinosa) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
MRVLVVPLPYPTHLMAMVPLCWALQASGHEVLIAAPPELQATAHGAGLTT
AGIRFPNPAFGQRDTEAGRQLWEQTASNVAQSSLDQLPEYLRLAEAWRPS
VLLVDVCALIGRVLGGLLDLPVVLHRWGVDPTAGPFSDRAHELLDPVCRH
HGLTGLPTPELILDPCPPSLQASDAPQGAPVQYVPYNGSGAFPAWGAART
SARRVCICMGRMVLNATGPAPLLRAVAAATELPGVEAVIAVPPEHRALLT
DLPDNARIAESVPLNLFLRTCELVICAGGSGTAFTATRLGIPQLVLPQYF
DQFDYARNLAAAGAGICLPDEQAQSDHEQFTDSIATVLGDTGFAAAAIKL
SDEITAMPHPAALVRTLEN
Ligand information
Ligand IDBGC
InChIInChI=1S/C6H12O6/c7-1-2-3(8)4(9)5(10)6(11)12-2/h2-11H,1H2/t2-,3-,4+,5-,6-/m1/s1
InChIKeyWQZGKKKJIJFFOK-VFUOTHLCSA-N
SMILES
SoftwareSMILES
OpenEye OEToolkits 1.7.6C(C1C(C(C(C(O1)O)O)O)O)O
CACTVS 3.370OC[C@H]1O[C@@H](O)[C@H](O)[C@@H](O)[C@@H]1O
CACTVS 3.370OC[CH]1O[CH](O)[CH](O)[CH](O)[CH]1O
OpenEye OEToolkits 1.7.6C([C@@H]1[C@H]([C@@H]([C@H]([C@@H](O1)O)O)O)O)O
ACDLabs 12.01OC1C(O)C(OC(O)C1O)CO
FormulaC6 H12 O6
Namebeta-D-glucopyranose;
beta-D-glucose;
D-glucose;
glucose
ChEMBLCHEMBL1614854
DrugBankDB02379
ZINCZINC000003833800
PDB chain3uyk Chain B Residue 388 [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
Receptor-Ligand Complex Structure
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PDB3uyk Structural Studies of the Spinosyn Rhamnosyltransferase, SpnG.
Resolution1.7 Å
Binding residue
(original residue number in PDB)		G76 Q77 R78 D79 D319
Binding residue
(residue number reindexed from 1)		G61 Q62 R63 D64 D304
Annotation score4
Enzymatic activity
Enzyme Commision number 2.4.1.-
Gene Ontology
Molecular Function
GO:0008194 UDP-glycosyltransferase activity
GO:0016740 transferase activity
GO:0016758 hexosyltransferase activity
Biological Process
GO:0017000 antibiotic biosynthetic process

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Molecular Function
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Biological Process
External links
PDB RCSB:3uyk, PDBe:3uyk, PDBj:3uyk
PDBsum3uyk
PubMed22283226
UniProtQ9ALM8

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