Structure of PDB 3ukm Chain B Binding Site BS02
Receptor Information
>3ukm Chain B (length=252) Species:
9606
(Homo sapiens) [
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NSATMFGFLVLGYLLYLVFGAVVFSSVELPYEDLLRQELRKLKRRFLEEH
ECLSEQQLEQFLGRVLEASNYGVSVLWNWDFTSALFFASTVLSTTGYGHT
VPLSDGGKAFCIIYSVIGIPFTLLFLTAVVQRITVHVTRRPVLYFSKQVV
AIVHAVLLGFVTVSCFFFIPAAVFSVLEDDWNFLESFYFCFISLSTIGLG
DYVPGEGYNQKFRELYKIGITCYLLLGLIAMLVVLETFCELHELKKFRKM
FY
Ligand information
Ligand ID
K
InChI
InChI=1S/K/q+1
InChIKey
NPYPAHLBTDXSSS-UHFFFAOYSA-N
SMILES
Software
SMILES
ACDLabs 10.04
CACTVS 3.341
OpenEye OEToolkits 1.5.0
[K+]
Formula
K
Name
POTASSIUM ION
ChEMBL
CHEMBL1233793
DrugBank
DB01345
ZINC
PDB chain
3ukm Chain A Residue 2 [
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Receptor-Ligand Complex Structure
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PDB
3ukm
Crystal structure of the human two-pore domain potassium channel K2P1.
Resolution
3.4 Å
Binding residue
(original residue number in PDB)
T118 G119 Y120 I226 G227 L228
Binding residue
(residue number reindexed from 1)
T95 G96 Y97 I197 G198 L199
Annotation score
5
Enzymatic activity
Enzyme Commision number
?
Gene Ontology
Molecular Function
GO:0005267
potassium channel activity
Biological Process
GO:0071805
potassium ion transmembrane transport
Cellular Component
GO:0016020
membrane
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Cellular Component
External links
PDB
RCSB:3ukm
,
PDBe:3ukm
,
PDBj:3ukm
PDBsum
3ukm
PubMed
22282804
UniProt
O00180
|KCNK1_HUMAN Potassium channel subfamily K member 1 (Gene Name=KCNK1)
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