Structure of PDB 3ubt Chain B Binding Site BS02

Receptor Information
>3ubt Chain B (length=328) Species: 197575 (Haemophilus aegyptius) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
MNLISLFSGAGGLDLGFQKAGFRIICANEYDKSIWKTYESNHSAKLIKGD
ISKISSDEFPKCDGIIGGPPSQSWSEGGSLRGIDDPRGKLFYEYIRILKQ
KKPIFFLAENVKGMMAQRHNKAVQEFIQEFDNAGYDVHIILLNANDYGVA
QDRKRVFYIGFRKELNINYLPPIPHLIKPTFKDVIWDLKDNPIPALDKNK
TNGNKCIYPNHEYFIGSYSTIFMSRNRVRQWNEPAFTVQASGRQCQLHPQ
APVMLKVSKNLNKFVEGKEHLYRRLTVRECARVQGFPDDFIFHYESLNDG
YKMIGNAVPVNLAYEIAKTIKSALEICK
Ligand information
Receptor-Ligand Complex Structure
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PDB3ubt Structural origins of DNA target selection and nucleobase extrusion by a DNA Cytosine methyltransferase.
Resolution2.502 Å
Binding residue
(original residue number in PDB)		R225 R227 T237 Q239 Q244
Binding residue
(residue number reindexed from 1)		R225 R227 T237 Q239 Q244
Enzymatic activity
Catalytic site (original residue number in PDB) S71 E109 R153 R155
Catalytic site (residue number reindexed from 1) S71 E109 R153 R155
Enzyme Commision number 2.1.1.37: DNA (cytosine-5-)-methyltransferase.
Gene Ontology
Molecular Function
GO:0003677 DNA binding
GO:0003886 DNA (cytosine-5-)-methyltransferase activity
GO:0005524 ATP binding
GO:0008168 methyltransferase activity
Biological Process
GO:0009307 DNA restriction-modification system
GO:0032259 methylation

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Molecular Function
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Biological Process
External links
PDB RCSB:3ubt, PDBe:3ubt, PDBj:3ubt
PDBsum3ubt
PubMed23012373
UniProtP20589|MTH3_HAEAE Type II methyltransferase M.HaeIII (Gene Name=haeIIIM)

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