Structure of PDB 3u94 Chain B Binding Site BS02

Receptor Information
>3u94 Chain B (length=253) Species: 10116 (Rattus norvegicus) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
RSLIVTTLLEEPFVMFRKSDRTLYGNDRFEGYCIDLLKELAHILGFSYEI
RLVEDGKYGAQDDKGQWNGMVKELIDHKADLAVAPLTITHVREKAIDFSK
PFMTLGVSILYRKGTPIDSADDLAKQTKIEYGAVKDGATMTFFKKSKIST
FEKMWAFMSSKPSALVKNNEEGIQRTLTADYALLMESTTIEYITQRNCNL
TQIGGLIDSKGYGIGTPMGSPYRDKITIAILQLQEEDKLHIMKEKWWRGS
GCP
Ligand information
Ligand IDZN
InChIInChI=1S/Zn/q+2
InChIKeyPTFCDOFLOPIGGS-UHFFFAOYSA-N
SMILES
SoftwareSMILES
CACTVS 3.341[Zn++]
ACDLabs 10.04
OpenEye OEToolkits 1.5.0		[Zn+2]
FormulaZn
NameZINC ION
ChEMBLCHEMBL1236970
DrugBankDB14532
ZINC
PDB chain3u94 Chain B Residue 259 [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
Receptor-Ligand Complex Structure
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PDB3u94 Zinc Potentiates GluK3 Glutamate Receptor Function by Stabilizing the Ligand Binding Domain Dimer Interface.
Resolution1.962 Å
Binding residue
(original residue number in PDB)		H243 E247
Binding residue
(residue number reindexed from 1)		H240 E244
Annotation score1
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Molecular Function
GO:0015276 ligand-gated monoatomic ion channel activity
Cellular Component
GO:0016020 membrane

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Molecular Function
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Cellular Component
External links
PDB RCSB:3u94, PDBe:3u94, PDBj:3u94
PDBsum3u94
PubMed23141068
UniProtP42264|GRIK3_RAT Glutamate receptor ionotropic, kainate 3 (Gene Name=Grik3)

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