Structure of PDB 3qhr Chain B Binding Site BS02

Receptor Information
>3qhr Chain B (length=261) Species: 10090 (Mus musculus) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
SNEVPDYQEDIHTYLREMEVKCKPKVGYMKRQPDITNSMRAILVDWLVEV
GEEYKLQNETLHLAVNYIDRFLSSMSVLRGKLQLVGTAAMLLASKFEEIY
PPEVAEFVYITDDTYSKKQVLRMEHLVLKVLAFDLAAPTVNQFLTQYFLH
LQPANCKVESLAMFLGELSLIDADPYLKYLPSLIAGAAFHLALYTVTGQS
WPESLAQQTGYTLESLKPCLVDLHQTYLKAPQHAQQSIREKYKHSKYHSV
SLLNPPETLSV
Ligand information
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

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PDB3qhr Briefly Bound to Activate: Transient Binding of a Second Catalytic Magnesium Activates the Structure and Dynamics of CDK2 Kinase for Catalysis.
Resolution2.17 Å
Binding residue
(original residue number in PDB)		E224 Y225 K226 Q254 Y271 E277 I281 T285
Binding residue
(residue number reindexed from 1)		E53 Y54 K55 Q83 Y100 E106 I110 T114
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Molecular Function
GO:0016538 cyclin-dependent protein serine/threonine kinase regulator activity
Biological Process
GO:0044772 mitotic cell cycle phase transition

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Molecular Function
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Biological Process
External links
PDB RCSB:3qhr, PDBe:3qhr, PDBj:3qhr
PDBsum3qhr
PubMed21565702
UniProtP51943|CCNA2_MOUSE Cyclin-A2 (Gene Name=Ccna2)

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