Structure of PDB 3pu8 Chain B Binding Site BS02

Receptor Information
>3pu8 Chain B (length=365) Species: 9606 (Homo sapiens) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
KPVQNGSQLFIKELRSRTFPSAEDVVARVPGSQLTLGYMEEHGFTEPILV
PKKDGLGLAVPAPTFYVSDVENYVGPERSVDVTDVTKQKDCKMKLKEFVD
YYYSTNRKRVLNVTNLEFSDTRMSSFVEPPDIVKKLSWVENYWPDDALLA
KPKVTKYCLICVKDSYTDFHIDSGGASAWYHVLKGEKTFYLIRPASANIS
LYERWRSASNHSEMFFADQVDKCYKCIVKQGQTLFIPSGWIYATLTPVDC
LAFAGHFLHSLSVEMQMRAYEVERRLKLGSLTQFPNFETACWYMGKHLLE
AFKGSHKSGKQLPPHLVQGAKILNGAFRSWTKKQALAEHEDELPEHFKPS
QLIKDLAKEIRLSEN
Ligand information
Ligand IDFE
InChIInChI=1S/Fe/q+3
InChIKeyVTLYFUHAOXGGBS-UHFFFAOYSA-N
SMILES
SoftwareSMILES
ACDLabs 10.04
CACTVS 3.341
OpenEye OEToolkits 1.5.0		[Fe+3]
FormulaFe
NameFE (III) ION
ChEMBL
DrugBankDB13949
ZINC
PDB chain3pu8 Chain B Residue 454 [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

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PDB3pu8 Structural basis for human PHF2 Jumonji domain interaction with metal ions.
Resolution1.943 Å
Binding residue
(original residue number in PDB)		H249 D251 Y321
Binding residue
(residue number reindexed from 1)		H170 D172 Y242
Annotation score1
Enzymatic activity
Enzyme Commision number 1.14.11.-
External links
PDB RCSB:3pu8, PDBe:3pu8, PDBj:3pu8
PDBsum3pu8
PubMed21167174
UniProtO75151|PHF2_HUMAN Lysine-specific demethylase PHF2 (Gene Name=PHF2)

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