Structure of PDB 3pqz Chain B Binding Site BS02

Receptor Information
>3pqz Chain B (length=105) Species: 9606 (Homo sapiens) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
AAIHRTQLWFHGRISREESQRLIGQQGLVDGLFLVRESQRNQGFVLSLCH
LQKVKHYLILPSEEGRLYFSMDDGQTRFTDLLQLVEFHQLNRGILPCLLR
HCCTR
Ligand information
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

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PDB3pqz Structural basis of binding by cyclic nonphosphorylated Peptide antagonists of grb7 implicated in breast cancer progression
Resolution2.413 Å
Binding residue
(original residue number in PDB)
R438 K478 H479 Y480 L481 L483 M495 D496 Q499
Binding residue
(residue number reindexed from 1)
R16 K55 H56 Y57 L58 L60 M71 D72 Q75
Enzymatic activity
Enzyme Commision number ?
External links
PDB RCSB:3pqz, PDBe:3pqz, PDBj:3pqz
PDBsum3pqz
PubMed21802427
UniProtQ14451|GRB7_HUMAN Growth factor receptor-bound protein 7 (Gene Name=GRB7)

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