Structure of PDB 3p7h Chain B Binding Site BS02

Receptor Information
>3p7h Chain B (length=130) Species: 9606 (Homo sapiens) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
SQGWKYFKGNFYYFSLIPKTWYSAEQFCVSRNSHLTSVTSESEQEFLYKT
AGGLIYWIGLTKAGMEGDWSWVDDTPFNKVQSVRFWIPGEPNNAGNNEHC
GNIKAPSLQAWNDAPCDKTFLFICKRPYVP
Ligand information
Ligand IDCA
InChIInChI=1S/Ca/q+2
InChIKeyBHPQYMZQTOCNFJ-UHFFFAOYSA-N
SMILES
SoftwareSMILES
CACTVS 3.341[Ca++]
ACDLabs 10.04
OpenEye OEToolkits 1.5.0		[Ca+2]
FormulaCa
NameCALCIUM ION
ChEMBL
DrugBankDB14577
ZINC
PDB chain3p7h Chain B Residue 1 [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

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PDB3p7h The carbohydrate recognition domain of Langerin reveals high structural similarity with the one of DC-SIGN but an additional, calcium-independent sugar-binding site.
Resolution2.3 Å
Binding residue
(original residue number in PDB)		E285 N287 E293 N307 D308
Binding residue
(residue number reindexed from 1)		E90 N92 E98 N112 D113
Annotation score4
Enzymatic activity
Enzyme Commision number ?
External links
PDB RCSB:3p7h, PDBe:3p7h, PDBj:3p7h
PDBsum3p7h
PubMed18061677
UniProtQ9UJ71|CLC4K_HUMAN C-type lectin domain family 4 member K (Gene Name=CD207)

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