Structure of PDB 3og8 Chain B Binding Site BS02
Receptor Information
>3og8 Chain B (length=128) Species:
9606
(Homo sapiens) [
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MDKENKKLLCRKCKALACYTADVRVIEESHYTVLGDAFKECFVSRPHPKP
KQFSSFEKRAKIFCARQNCSHDWGIHVKYKTFEIPVIKIESFVVEDIATG
VQTLYSKWKDFHFEKIPFDPAEMSKLEH
Ligand information
>3og8 Chain D (length=14) [
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ggcgcgcgcgcgcc
..............
Receptor-Ligand Complex Structure
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PDB
3og8
Crystal structure of RIG-I C-terminal domain bound to blunt-ended double-strand RNA without 5' triphosphate.
Resolution
2.4 Å
Binding residue
(original residue number in PDB)
H830 F853 K858 G874 I875 V886 K888 K907 W908
Binding residue
(residue number reindexed from 1)
H30 F53 K58 G74 I75 V86 K88 K107 W108
Enzymatic activity
Enzyme Commision number
3.6.4.13
: RNA helicase.
External links
PDB
RCSB:3og8
,
PDBe:3og8
,
PDBj:3og8
PDBsum
3og8
PubMed
20961956
UniProt
O95786
|RIGI_HUMAN Antiviral innate immune response receptor RIG-I (Gene Name=RIGI)
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