Structure of PDB 3o72 Chain B Binding Site BS02

Receptor Information
>3o72 Chain B (length=375) Species: 544404 (Escherichia coli O157:H7 str. TW14359) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
VARNEKQPFYGEHQAGILTPQQAAMMLVAFDVLASDKADLERLFRLLTQR
FAFLTQGGAAPETPNPRLPPLDSGILGGYIAPDNLTITLSVGHSLFDERF
GLAPQMPKKLQKMTRFPNDSLDAALCHGDVLLQICANTQDTVIHALRDII
KHTPDLLSVRWKREGFISDHAARSKGKETPINLLGFKDGTANPDSQNDKL
MQKVVWVTADQQEPAWTIGGSYQAVRLIQFRVEFWDRTPLKEQQTIFGRD
KQTGAPLGMQHEHDVPDYASDPEGKGIALDSHIRLANPRTAESESSLMLR
RGYSYSLGVTNSGQLDMGLLFVCYQHDLEKGFLTVQKRLNGEALEEYVKP
IGGGYFFALPGVKDANDYLGSALLR
Ligand information
Ligand IDOXY
InChIInChI=1S/O2/c1-2
InChIKeyMYMOFIZGZYHOMD-UHFFFAOYSA-N
SMILES
SoftwareSMILES
CACTVS 3.341
OpenEye OEToolkits 1.5.0		O=O
FormulaO2
NameOXYGEN MOLECULE
ChEMBLCHEMBL1234886
DrugBankDB09140
ZINC
PDB chain3o72 Chain B Residue 600 [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
Receptor-Ligand Complex Structure
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PDB3o72 Crystal structure and biochemical features of EfeB/YcdB from Escherichia coli O157: ASP235 plays divergent roles in different enzyme-catalyzed processes
Resolution1.95 Å
Binding residue
(original residue number in PDB)		D235 R347
Binding residue
(residue number reindexed from 1)		D188 R300
Annotation score1
Enzymatic activity
Enzyme Commision number 1.11.1.-
4.98.1.1: protoporphyrin ferrochelatase.
Gene Ontology
Molecular Function
GO:0004325 ferrochelatase activity
GO:0004601 peroxidase activity
GO:0016829 lyase activity
GO:0020037 heme binding
GO:0046872 metal ion binding
Biological Process
GO:0033212 iron import into cell
GO:0098869 cellular oxidant detoxification
Cellular Component
GO:0005829 cytosol
GO:0042597 periplasmic space

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Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:3o72, PDBe:3o72, PDBj:3o72
PDBsum3o72
PubMed21324904
UniProtQ8XAS4|EFEB_ECO57 Deferrochelatase (Gene Name=efeB)

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