Structure of PDB 3ngz Chain B Binding Site BS02

Receptor Information
>3ngz Chain B (length=206) Species: 562 (Escherichia coli) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
TGLCDRFRGFYPVVIDVETAGFNAKTDALLEIAAITLKMDEQGWLMPDTT
LHFHVEPFVGANLQPEALAFNGIDPNDPDRGAVSGYEALHEIFKVVRKGI
KASGCNRAIMVAHNANFDHSFMMAAAERASLKRNPFHPFATFDTAALAGL
ALGQTVLSKACQTAGMDFDSTQAHSALYDTERTAVLFCEIVNRWKRLGGW
PLSAAE
Ligand information
Ligand IDCO
InChIInChI=1S/Co/q+2
InChIKeyXLJKHNWPARRRJB-UHFFFAOYSA-N
SMILES
SoftwareSMILES
ACDLabs 10.04
OpenEye OEToolkits 1.5.0		[Co+2]
CACTVS 3.341[Co++]
FormulaCo
NameCOBALT (II) ION
ChEMBL
DrugBankDB14205
ZINC
PDB chain3ngz Chain B Residue 217 [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

[Spin on] [Spin off] [Reset]
[High quality] [Low quality]
[White background] [Black background]
[Spin on] [Spin off] [Reset]
[High quality] [Low quality]
[White background] [Black background]
PDB3ngz Structural basis for RNA trimming by RNase T in stable RNA 3'-end maturation
Resolution2.1 Å
Binding residue
(original residue number in PDB)		F65 R135
Binding residue
(residue number reindexed from 1)		F58 R128
Annotation score3
Enzymatic activity
Enzyme Commision number 3.1.13.-
Gene Ontology
Molecular Function
GO:0000175 3'-5'-RNA exonuclease activity
GO:0000287 magnesium ion binding
GO:0003676 nucleic acid binding
GO:0004527 exonuclease activity
GO:0004540 RNA nuclease activity
GO:0005515 protein binding
GO:0008310 single-stranded DNA 3'-5' DNA exonuclease activity
GO:0008408 3'-5' exonuclease activity
GO:0016896 RNA exonuclease activity, producing 5'-phosphomonoesters
GO:0042802 identical protein binding
GO:0042803 protein homodimerization activity
GO:0046872 metal ion binding
Biological Process
GO:0006259 DNA metabolic process
GO:0006396 RNA processing
GO:0006974 DNA damage response
GO:0008033 tRNA processing
GO:0031125 rRNA 3'-end processing
GO:0034644 cellular response to UV
GO:0042780 tRNA 3'-end processing
GO:0043628 regulatory ncRNA 3'-end processing
GO:0045004 DNA replication proofreading
Cellular Component
GO:0005829 cytosol

View graph for
Molecular Function
View graph for
Biological Process
View graph for
Cellular Component
External links
PDB RCSB:3ngz, PDBe:3ngz, PDBj:3ngz
PDBsum3ngz
PubMed21317904
UniProtP30014|RNT_ECOLI Ribonuclease T (Gene Name=rnt)

[Back to BioLiP]