Structure of PDB 3kik Chain B Binding Site BS02

Receptor Information
>3kik Chain B (length=92) Species: 4932 (Saccharomyces cerevisiae) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
DTAQLKSQIQQYLVESGNYELISNELKARLLQEGWVDKVKDLTKSEMNIN
ESTNFTQILSTVEPKALEMVSDSTRETVLKQIREFLEEIVDT
Ligand information
>3kik Chain F (length=27) Species: 4932 (Saccharomyces cerevisiae) [Search peptide sequence] [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
STIDSISNGILNNLLTTLIQDIVARET
Receptor-Ligand Complex Structure
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PDB3kik Structural basis for the interaction between yeast Spt-Ada-Gcn5 acetyltransferase (SAGA) complex components Sgf11 and Sus1
Resolution2.1 Å
Binding residue
(original residue number in PDB)		I12 Q13 Y22 W38 V39 V42 T46 K47 M50 F58 L70 R78 L82 I85
Binding residue
(residue number reindexed from 1)		I9 Q10 Y19 W35 V36 V39 T43 K44 M47 F55 L67 R75 L79 I82
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Molecular Function
GO:0003682 chromatin binding
GO:0003713 transcription coactivator activity
GO:0005515 protein binding
GO:0008047 enzyme activator activity
Biological Process
GO:0000973 post-transcriptional tethering of RNA polymerase II gene DNA at nuclear periphery
GO:0006325 chromatin organization
GO:0006357 regulation of transcription by RNA polymerase II
GO:0006368 transcription elongation by RNA polymerase II
GO:0006406 mRNA export from nucleus
GO:0015031 protein transport
GO:0016973 poly(A)+ mRNA export from nucleus
GO:0032880 regulation of protein localization
GO:0045893 positive regulation of DNA-templated transcription
GO:0045944 positive regulation of transcription by RNA polymerase II
GO:0051028 mRNA transport
GO:0071028 nuclear mRNA surveillance
Cellular Component
GO:0000124 SAGA complex
GO:0000932 P-body
GO:0005634 nucleus
GO:0005643 nuclear pore
GO:0005654 nucleoplasm
GO:0005737 cytoplasm
GO:0046695 SLIK (SAGA-like) complex
GO:0070390 transcription export complex 2
GO:0071819 DUBm complex

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Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:3kik, PDBe:3kik, PDBj:3kik
PDBsum3kik
PubMed20007317
UniProtQ6WNK7|SUS1_YEAST Transcription and mRNA export factor SUS1 (Gene Name=SUS1)

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