Structure of PDB 3gli Chain B Binding Site BS02

Receptor Information

>3gli Chain B (length=359) Species: 83333 (Escherichia coli K-12)

VLARKWRPQTFADVVGQEHVLTALANGLSLGRIHHAYLFSGTRGVGKTSI
ARLLAKGLNCETGITATPCGVCDNCREIEQGRFVDLIEIDAASRTKVEDT
RDLLDNVQYAPARGRFKVYLIDEVHMLSRHSFNALLKTLEEPPEHVKFLL
ATTDPQKLPVTILSRCLQFHLKALDVEQIRHQLEHILNEEHIAHEPRALQ
LLARAAEGSLRDALSLTDQAIASGDGQVSTQAVSAMLGTLDDDQALSLVE
AMVEANGERVMALINEAAARGIEWEALLVEMLGLLHRIAMVQLSPAALGN
DMAAIELRMRELARTIPPTDIQLYYQTLLIGRKELPYAPDRRMGVEMTLL
RALAFHPRM

Ligand information

>3gli Chain O (length=27) Species: 83333 (Escherichia coli K-12)

TSRRDWQLQQLGITQWSLRRPGALQGE

Receptor-Ligand Complex Structure

Structure summary

• PDB: 3gli The mechanism of ATP-dependent primer-template recognition by a clamp loader complex.
• Resolution: 3.5 Å
• Binding residue (original residue number in PDB): L327 Y328 T331 R355 L357 A358 F359 H360 P361 R362
• Binding residue (residue number reindexed from 1): L323 Y324 T327 R351 L353 A354 F355 H356 P357 R358

Enzymatic activity

• Enzyme Commision number: 2.7.7.7: DNA-directed DNA polymerase.

Gene Ontology

Molecular Function

• GO:0003677 DNA binding
• GO:0003887 DNA-directed DNA polymerase activity
• GO:0005524 ATP binding
• GO:0016887 ATP hydrolysis activity

Biological Process

• GO:0006260 DNA replication

Cellular Component

• GO:0009360 DNA polymerase III complex

External links

• PDB: RCSB:3gli, PDBe:3gli, PDBj:3gli
• PDBsum: 3gli
• PubMed: 19450514
• UniProt: P06710|DPO3X_ECOLI DNA polymerase III subunit tau (Gene Name=dnaX)