Structure of PDB 3g5k Chain B Binding Site BS02

Receptor Information
>3g5k Chain B (length=183) Species: 9606 (Homo sapiens) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
HMSFSHVCQVGDPVLRGVAAPVERAQLGGPELQRLTQRLVQVMRRRRCVG
LSAPQLGVPRQVLALELPEALCRECPPRQRALRQMEPFPLRVFVNPSLRV
LDSRLVTFPEGCESVAGFLACVPRFQAVQISGLDPNGEQVVWQASGWAAR
IIQHEMDHLQGCLFIDKMDSRTFTNVYWMKVND
Ligand information
Ligand IDCO
InChIInChI=1S/Co/q+2
InChIKeyXLJKHNWPARRRJB-UHFFFAOYSA-N
SMILES
SoftwareSMILES
ACDLabs 10.04
OpenEye OEToolkits 1.5.0		[Co+2]
CACTVS 3.341[Co++]
FormulaCo
NameCOBALT (II) ION
ChEMBL
DrugBankDB14205
ZINC
PDB chain3g5k Chain B Residue 1003 [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

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PDB3g5k Structure and activity of human mitochondrial peptide deformylase, a novel cancer target
Resolution1.7 Å
Binding residue
(original residue number in PDB)		Q57 C114 H156 H160
Binding residue
(residue number reindexed from 1)		Q55 C112 H154 H158
Annotation score1
Enzymatic activity
Catalytic site (original residue number in PDB) G52 Q57 C114 E115 H156 E157 H160
Catalytic site (residue number reindexed from 1) G50 Q55 C112 E113 H154 E155 H158
Enzyme Commision number 3.5.1.88: peptide deformylase.
Gene Ontology
Molecular Function
GO:0042586 peptide deformylase activity

View graph for
Molecular Function
External links
PDB RCSB:3g5k, PDBe:3g5k, PDBj:3g5k
PDBsum3g5k
PubMed19236878
UniProtQ9HBH1|DEFM_HUMAN Peptide deformylase, mitochondrial (Gene Name=PDF)

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