Structure of PDB 3fyl Chain B Binding Site BS02

Receptor Information
>3fyl Chain B (length=76) Species: 10116 (Rattus norvegicus) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
SHMCLVCSDEASGCHYGVLTCGSCKVFFKRAVEGQHNYLCAGRNDCIIDK
IRRKNCPACRYRKCLQAGMNLEARKT
Ligand information
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

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PDB3fyl DNA binding site sequence directs glucocorticoid receptor structure and activity.
Resolution1.63 Å
Binding residue
(original residue number in PDB)		C450 H451 Y452 K461 K465 K490 R510
Binding residue
(residue number reindexed from 1)		C14 H15 Y16 K25 K29 K54 R74
Binding affinityPDBbind-CN: Kd=0.24uM
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Molecular Function
GO:0003700 DNA-binding transcription factor activity
GO:0008270 zinc ion binding
GO:0043565 sequence-specific DNA binding
Biological Process
GO:0006355 regulation of DNA-templated transcription

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Molecular Function
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Biological Process
External links
PDB RCSB:3fyl, PDBe:3fyl, PDBj:3fyl
PDBsum3fyl
PubMed19372434
UniProtP06536|GCR_RAT Glucocorticoid receptor (Gene Name=Nr3c1)

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