Structure of PDB 3f2o Chain B Binding Site BS02

Receptor Information
>3f2o Chain B (length=204) Species: 9606 (Homo sapiens) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
DYCKPTRLDLLLDMPPVSYDVQLLHSWNNNDRSLNVFVKEDDKLIFHRHP
VAQSTDAIRGKVGYTRGLHVWQITWAMRQRGTHAVVGVATADAPLHSVGY
TTLVGNNHESWGWDLGRNRLYHDGKNQPSKTYPAFLEPDETFIVPDSFLV
ALDMDDGTLSFIVDGQYMGVAFRGLKGKKLYPVVSAVWGHCEIRMRYLNG
LDPE
Ligand information
>3f2o Chain D (length=15) Species: 7227 (Drosophila melanogaster) [Search peptide sequence] [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
DINNNNNIVEDVERK
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

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PDB3f2o Structural basis for Par-4 recognition by the SPRY domain- and SOCS box-containing proteins SPSB1, SPSB2, and SPSB4.
Resolution2.05 Å
Binding residue
(original residue number in PDB)		S62 L63 N64 R77 P79 V80 A81 G110 T111 H125 Y129 V216 W217 G218
Binding residue
(residue number reindexed from 1)		S33 L34 N35 R48 P50 V51 A52 G81 T82 H96 Y100 V187 W188 G189
Enzymatic activity
Enzyme Commision number ?
External links
PDB RCSB:3f2o, PDBe:3f2o, PDBj:3f2o
PDBsum3f2o
PubMed20561531
UniProtQ96BD6|SPSB1_HUMAN SPRY domain-containing SOCS box protein 1 (Gene Name=SPSB1)

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