Structure of PDB 3erd Chain B Binding Site BS02
Receptor Information
>3erd Chain B (length=237) Species:
9606
(Homo sapiens) [
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SLALSLTADQMVSALLDAEPPILYSEYDPTRPFSEASMMGLLTNLADREL
VHMINWAKRVPGFVDLTLHDQVHLLECAWLEILMIGLVWRSMEHPGKLLF
APNLLLDRNQGKCVEGMVEIFDMLLATSSRFRMMNLQGEEFVCLKSIILL
NSGVYTFEEKDHIHRVLDKITDTLIHLMAKAGLTLQQQHQRLAQLLLILS
HIRHMSNKGMEHLYSMKCKNVVPLYDLLLEMLDAHRL
Ligand information
>3erd Chain D (length=11) Species:
9606
(Homo sapiens) [
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KHKILHRLLQD
Receptor-Ligand Complex Structure
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PDB
3erd
The structural basis of estrogen receptor/coactivator recognition and the antagonism of this interaction by tamoxifen.
Resolution
2.03 Å
Binding residue
(original residue number in PDB)
I358 K362 V376 E380 E542
Binding residue
(residue number reindexed from 1)
I54 K58 V72 E76 E230
Enzymatic activity
Enzyme Commision number
?
External links
PDB
RCSB:3erd
,
PDBe:3erd
,
PDBj:3erd
PDBsum
3erd
PubMed
9875847
UniProt
P03372
|ESR1_HUMAN Estrogen receptor (Gene Name=ESR1)
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