Structure of PDB 3eqt Chain B Binding Site BS02
Receptor Information
>3eqt Chain B (length=142) Species:
9606
(Homo sapiens) [
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RQQFPVEHVQLLCINCMVAVGHGSDLRKVEGTHHVNVNPNFSNYYNVSRD
PVVINKVFKDWKPGGVISCRNCGEVWGLQMIYKSVKLPVLKVRSMLLETP
QGRIQAKKWSRVPFSVPDFDFLQHCAENLSDLSLDLEHHHHH
Ligand information
>3eqt Chain D (length=8) [
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gcgcgcgc
........
Receptor-Ligand Complex Structure
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PDB
3eqt
The RIG-I-like Receptor LGP2 Recognizes the Termini of Double-stranded RNA
Resolution
2.0 Å
Binding residue
(original residue number in PDB)
T575 H576 V595 I597 G620 L621 K634 V635 K651 W652 S653
Binding residue
(residue number reindexed from 1)
T32 H33 V52 I54 G77 L78 K91 V92 K108 W109 S110
Binding affinity
PDBbind-CN
: Kd=105nM
Enzymatic activity
Enzyme Commision number
3.6.4.13
: RNA helicase.
External links
PDB
RCSB:3eqt
,
PDBe:3eqt
,
PDBj:3eqt
PDBsum
3eqt
PubMed
19278996
UniProt
Q96C10
|DHX58_HUMAN ATP-dependent RNA helicase DHX58 (Gene Name=DHX58)
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