Structure of PDB 3ehj Chain B Binding Site BS02

Receptor Information
>3ehj Chain B (length=211) Species: 1423 (Bacillus subtilis) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
ERERLEEKLEDANERIAELVKLEERQRMARDLVDTLGQKLSLMGLKSDLA
RKLIYKDPEQAARELKSVQQTARTSLNEVRKIVSSMKGIRLKDELINIKQ
ILEAADIMFIYEEEKWPENISLLNENILSMCLKEAVTNVVKHSQAKTCRV
DIQQLWKEVVITVSDDGTFKGEENSFHGLLGMRERLEFANGSLHIDTENG
TKLTMAIPNNS
Ligand information
Ligand IDCA
InChIInChI=1S/Ca/q+2
InChIKeyBHPQYMZQTOCNFJ-UHFFFAOYSA-N
SMILES
SoftwareSMILES
CACTVS 3.341[Ca++]
ACDLabs 10.04
OpenEye OEToolkits 1.5.0		[Ca+2]
FormulaCa
NameCALCIUM ION
ChEMBL
DrugBankDB14577
ZINC
PDB chain3ehj Chain B Residue 1 [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

[Spin on] [Spin off] [Reset]
[High quality] [Low quality]
[White background] [Black background]
[Spin on] [Spin off] [Reset]
[High quality] [Low quality]
[White background] [Black background]
PDB3ehj Structural plasticity and catalysis regulation of a thermosensor histidine kinase
Resolution2.5 Å
Binding residue
(original residue number in PDB)		E289 N293
Binding residue
(residue number reindexed from 1)		E134 N138
Annotation score4
Enzymatic activity
Enzyme Commision number 2.7.13.3: histidine kinase.
Gene Ontology
Molecular Function
GO:0000155 phosphorelay sensor kinase activity
GO:0046983 protein dimerization activity
Biological Process
GO:0000160 phosphorelay signal transduction system
Cellular Component
GO:0016020 membrane

View graph for
Molecular Function
View graph for
Biological Process
View graph for
Cellular Component
External links
PDB RCSB:3ehj, PDBe:3ehj, PDBj:3ehj
PDBsum3ehj
PubMed19805278
UniProtO34757|DESK_BACSU Sensor histidine kinase DesK (Gene Name=desK)

[Back to BioLiP]