Structure of PDB 3e45 Chain B Binding Site BS02

Receptor Information
>3e45 Chain B (length=249) Species: 727 (Haemophilus influenzae) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
SFIKPIYQDINSILIGQKVKRGHAAGEPFEKLVYKFLKENLSDLTFKQYE
YLNDLFMKNPAIIGHEARYKLFNSPTLLFLLSRGKAATENWSIENLFEEK
QNDTADILLVKDQFYELLDVKTRNISKSAFAPNIISAYKLAQTCAKMIDN
KEFDLFDINYLEVDWELNGEDLVCVSTSFAELFKSEPSELYINWAAAMQI
QFHVRDLDQGFNGTREEWAKSYLKHFVTQAEQRAISMIDKFVKPFKKYI
Ligand information
Receptor-Ligand Complex Structure
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PDB3e45 DNA distortion and specificity in a sequence-specific endonuclease.
Resolution2.78 Å
Binding residue
(original residue number in PDB)		H31 G92 K93 F138 Y199 N201 A203 A204 R241
Binding residue
(residue number reindexed from 1)		H23 G84 K85 F130 Y191 N193 A195 A196 R233
Enzymatic activity
Enzyme Commision number 3.1.21.4: type II site-specific deoxyribonuclease.
Gene Ontology
Molecular Function
GO:0003677 DNA binding
GO:0004519 endonuclease activity
GO:0009036 type II site-specific deoxyribonuclease activity
Biological Process
GO:0009307 DNA restriction-modification system

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Molecular Function
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Biological Process
External links
PDB RCSB:3e45, PDBe:3e45, PDBj:3e45
PDBsum3e45
PubMed18762194
UniProtP17743|T2C2_HAEIF Type II restriction enzyme HincII (Gene Name=hincIIR)

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