Structure of PDB 3e43 Chain B Binding Site BS02

Receptor Information
>3e43 Chain B (length=240) Species: 727 (Haemophilus influenzae) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
SFIKPIYQDINSILIGQKPFEKLVYKFLKENLSDLTFKQYEYLNDLFMKN
PAIIGHEARYKLFNSPTLLFLLSRGKAATENWSIENLFEEKQNDTADILL
VKDQFYELLDVKTRNISKSAFAPNIISAYKLAQTCAKMIDNKEFDLFDIN
YLEVDWELNGEDLVCVSTSFAELFKSEPSELYINWAAAMQIQFHVRDLDQ
GFNGTREEWAKSYLKHFVTQAEQRAISMIDKFVKPFKKYI
Ligand information
Receptor-Ligand Complex Structure
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PDB3e43 DNA distortion and specificity in a sequence-specific endonuclease.
Resolution2.73 Å
Binding residue
(original residue number in PDB)
K93 F138 Y199 N201 A203 A204 R241
Binding residue
(residue number reindexed from 1)
K76 F121 Y182 N184 A186 A187 R224
Enzymatic activity
Enzyme Commision number 3.1.21.4: type II site-specific deoxyribonuclease.
Gene Ontology
Molecular Function
GO:0003677 DNA binding
GO:0004519 endonuclease activity
GO:0009036 type II site-specific deoxyribonuclease activity
Biological Process
GO:0009307 DNA restriction-modification system

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Molecular Function

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Biological Process
External links
PDB RCSB:3e43, PDBe:3e43, PDBj:3e43
PDBsum3e43
PubMed18762194
UniProtP17743|T2C2_HAEIF Type II restriction enzyme HincII (Gene Name=hincIIR)

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