Structure of PDB 3e41 Chain B Binding Site BS02

Receptor Information

>3e41 Chain B (length=243) Species: 727 (Haemophilus influenzae) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]

SFIKPIYQDINSILIGQKVGEPFEKLVYKFLKENLSDLTFKQYEYLNDLF
MKNPAIIGHEARYKLFNSPTLLFLLSRGKAATENWSIENLFEEKQNDTAD
ILLVKDQFYELLDVKTRNISKSAFAPNIISAYKLAQTCAKMIDNKEFDLF
DINYLEVDWELNGEDLVCVSTSFAELFKSEPSELYINWAAAMQIQFHVRD
LDQGFNGTREEWAKSYLKHFVTQAEQRAISMIDKFVKPFKKYI

Ligand information

>3e41 Chain F (length=14) [Search DNA sequence] [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]

gccggtcgaccggc

Receptor-Ligand Complex Structure

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Structure summary

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PDB	3e41 DNA distortion and specificity in a sequence-specific endonuclease.
Resolution	2.73 Å
Binding residue (original residue number in PDB)	K93 F138 Y199 N201 A203 A204 R241 K248
Binding residue (residue number reindexed from 1)	K79 F124 Y185 N187 A189 A190 R227 K234

Enzymatic activity

Enzyme Commision number

3.1.21.4: type II site-specific deoxyribonuclease.

Gene Ontology

	Molecular Function
GO:0003677	DNA binding
GO:0004519	endonuclease activity
GO:0009036	type II site-specific deoxyribonuclease activity

	Biological Process
GO:0009307	DNA restriction-modification system

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Biological Process

External links

PDB	RCSB:3e41, PDBe:3e41, PDBj:3e41
PDBsum	3e41
PubMed	18762194
UniProt	P17743\|T2C2_HAEIF Type II restriction enzyme HincII (Gene Name=hincIIR)

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