Structure of PDB 3e40 Chain B Binding Site BS02

Receptor Information
>3e40 Chain B (length=241) Species: 727 (Haemophilus influenzae) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
SFIKPIYQDINSILIGQKVKREKLVYKFLKENLSDLTFKQYEYLNDLFMK
NPAIIGHEARYKLFNSPTLLFLLSRGKAATENWSIENLFEEKNDTADILL
VKDQFYELLDVKTRNISKSAFAPNIISAYKLAQTCAKMIDNKEFDLFDIN
YLEVDWELNGEDLVCVSTSFAELFKSEPSELYINWAAAMQIQFHVRDLDQ
GFNGTREEWAKSYLKHFVTQAEQRAISMIDKFVKPFKKYIL
Ligand information
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

[Spin on] [Spin off] [Reset]
[High quality] [Low quality]
[White background] [Black background]
[Spin on] [Spin off] [Reset]
[High quality] [Low quality]
[White background] [Black background]
PDB3e40 DNA distortion and specificity in a sequence-specific endonuclease.
Resolution2.1 Å
Binding residue
(original residue number in PDB)		G92 K93 F138 Y199 N201 A203 A204 R241 K248
Binding residue
(residue number reindexed from 1)		G76 K77 F121 Y182 N184 A186 A187 R224 K231
Enzymatic activity
Enzyme Commision number 3.1.21.4: type II site-specific deoxyribonuclease.
Gene Ontology
Molecular Function
GO:0003677 DNA binding
GO:0004519 endonuclease activity
GO:0009036 type II site-specific deoxyribonuclease activity
Biological Process
GO:0009307 DNA restriction-modification system

View graph for
Molecular Function
View graph for
Biological Process
External links
PDB RCSB:3e40, PDBe:3e40, PDBj:3e40
PDBsum3e40
PubMed18762194
UniProtP17743|T2C2_HAEIF Type II restriction enzyme HincII (Gene Name=hincIIR)

[Back to BioLiP]