Structure of PDB 3do7 Chain B Binding Site BS02

Receptor Information
>3do7 Chain B (length=293) Species: 9606 (Homo sapiens) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
GPYLVIVEQPKQRGFRFRYGCEGPSHGGLPGASSEKGRKTYPTVKICNYE
GPAKIEVDLVTHSDPPRAHAHSLVGKQCSELGICAVSVGPKDMTAQFNNL
GVLHVTKKNMMGTMIQKLQRQRLRSRPQGLTEAEQRELEQEAKELKKVMD
LSIVRLRFSAFLRDSDGSFSLPLKPVISQPIHDSKSPGASNLKISRMDKT
AGSVRGGDEVYLLCDKVQKDDIEVRFYEDDENGWQAFGDFSPTDVHKQYA
IVFRTPPYHKMKIERPVTVFLQLKRKRGGDVSDSKQFTYYPLV
Ligand information
Receptor-Ligand Complex Structure
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PDB3do7 NF-kapppaB p52:RelB heterodimer uses different binding modes to recognize different kappaB DNA
Resolution3.05 Å
Binding residue
(original residue number in PDB)		R52 Y55 C57 T142 K143 P223 Q254
Binding residue
(residue number reindexed from 1)		R16 Y19 C21 T106 K107 P187 Q218
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Molecular Function
GO:0003677 DNA binding
GO:0003700 DNA-binding transcription factor activity
Biological Process
GO:0006355 regulation of DNA-templated transcription
Cellular Component
GO:0005737 cytoplasm

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Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:3do7, PDBe:3do7, PDBj:3do7
PDBsum3do7
PubMed
UniProtQ00653|NFKB2_HUMAN Nuclear factor NF-kappa-B p100 subunit (Gene Name=NFKB2)

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