Structure of PDB 2zzn Chain B Binding Site BS02

Receptor Information
>2zzn Chain B (length=335) Species: 2190 (Methanocaldococcus jannaschii) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
PLCLKINKKHGEQTRRILIENNLLNKDYKITSEGNYLYLPIKDVDEDILK
SILNIEFELVDKELEEKKIIKKPSFREIISKKYRKEIDEGLISLSYDVVG
DLVILQISDEVDEKIRKEIGELAYKLIPCKGVFRRKSEVKGEFRVRELEH
LAGENRTLTIHKENGYRLWVDIAKVYFSPRLGGERARIMKKVSLNDVVVD
MFAGVGPFSIACKNAKKIYAIDINPHAIELLKKNIKLNKLEHKIIPILSD
VREVDVKGNRVIMNLPKFAHKFIDKALDIVEEGGVIHYYTIGKDFDKAIK
LFEKKCDCEVLEKRIVKSYAPREYILALDFKINKK
Ligand information
>2zzn Chain D (length=71) [Search RNA sequence] [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
gccgggguagucuaggggcuaggcagcggacugcagauccgccuuacgug
gguucaaaucccacccccggc
<<<<<<<..<<<<.......>>>>.<<<<<.......>>>>>.....<<<
<<.......>>>>>>>>>>>>
Receptor-Ligand Complex Structure
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PDB2zzn Tertiary structure checkpoint at anticodon loop modification in tRNA functional maturation.
Resolution2.95 Å
Binding residue
(original residue number in PDB)		K9 G12 E13 R16 K30 I31 L38 K68 R77 L95 S96 Q107 R136 E139 V140 R145 R147 K163 N165 G166 Y177 R181 P267 K318 S319 Y320 A321 P322 R323
Binding residue
(residue number reindexed from 1)		K8 G11 E12 R15 K29 I30 L37 K67 R76 L94 S95 Q106 R135 E138 V139 R144 R146 K162 N164 G165 Y176 R180 P266 K317 S318 Y319 A320 P321 R322
Enzymatic activity
Enzyme Commision number 2.1.1.228: tRNA (guanine(37)-N(1))-methyltransferase.
Gene Ontology
Molecular Function
GO:0008168 methyltransferase activity
GO:0008175 tRNA methyltransferase activity
GO:0016740 transferase activity
GO:0052906 tRNA (guanine(37)-N1)-methyltransferase activity
Biological Process
GO:0002939 tRNA N1-guanine methylation
GO:0008033 tRNA processing
GO:0030488 tRNA methylation
GO:0032259 methylation
Cellular Component
GO:0005737 cytoplasm

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Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:2zzn, PDBe:2zzn, PDBj:2zzn
PDBsum2zzn
PubMed19749755
UniProtQ58293|TRM5B_METJA tRNA (guanine(37)-N1)-methyltransferase Trm5b (Gene Name=trm5b)

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