Structure of PDB 2zo1 Chain B Binding Site BS02
Receptor Information
>2zo1 Chain B (length=206) Species:
10090
(Mus musculus) [
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HMPANHFGPIPGVPVGTMWRFRVQVSESGVHRPHVAGIHGRSNDGAYSLV
LAGGYEDDVDNGNYFTYTGSGGRDLSGNKRTAGQSSDQKLTNNNRALALN
CHSPINEKGAEAEDWRQGKPVRVVRNMKGGKHSKYAPAEGNRYDGIYKVV
KYWPERGKSGFLVWRYLLRRDDTEPEPWTREGKDRTRQLGLTMQYPEGYL
EALANK
Ligand information
>2zo1 Chain E (length=12) [
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gtcagcgcaatg
Receptor-Ligand Complex Structure
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PDB
2zo1
The SRA domain of UHRF1 flips 5-methylcytosine out of the DNA helix
Resolution
1.96 Å
Binding residue
(original residue number in PDB)
F437 R438 H450 V451 A452 G453 A468 G470 Y471 D474 Y483 T484 S486 R496 Y615
Binding residue
(residue number reindexed from 1)
F21 R22 H34 V35 A36 G37 A52 G54 Y55 D58 Y67 T68 S70 R80 Y199
Enzymatic activity
Enzyme Commision number
2.3.2.27
: RING-type E3 ubiquitin transferase.
External links
PDB
RCSB:2zo1
,
PDBe:2zo1
,
PDBj:2zo1
PDBsum
2zo1
PubMed
18772888
UniProt
Q8VDF2
|UHRF1_MOUSE E3 ubiquitin-protein ligase UHRF1 (Gene Name=Uhrf1)
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