Structure of PDB 2ycb Chain B Binding Site BS02

Receptor Information
>2ycb Chain B (length=635) Species: 187420 (Methanothermobacter thermautotrophicus str. Delta H) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
VSEMLEEIKRTIMQRLPERVQVAKVEFEGPEVVIYTKNPEIITENGNLIR
DIAKDIRKRIIIRSDRSVLMDPEKAIRKIHEIVPEEAKITNISFDDVTCE
VIIEARKPGLVIGKYGSTSREIVKNTGWAPKILRTPPISSEIIERIRRTL
RKNSKERKKILQQLGNRIHQKPKYDNDWARLTAMGGFREVGRSCLYLQTP
NSRVLLDCGVNVAGGDDKNSYPYLNVPEFTLDSLDAVIITHAHLDHSGFL
PYLYHYGYDGPVYCTAPTRDLMTLLQLDHIDIAHREDEPLPFNVKHVKKS
VKHTITLDYGEVTDIAPDIRLTLHNAGHILGSAMAHLHIGDGQHNMVYTG
DFKYEQSRLLEAAANRFPRIETLVMESTYGGHEDVQPSRNRAEKELVKTI
YSTLRRGGKILIPVFAVGRAQELMIVLEEYIRTGIIDEVPVYIDGMIWEA
NAIHTARPEYLSKDLRDQIFHMGHNPFISDIFHKVNGMDERREIVEGEPS
IILSTSGMLTGGNSLEYFKWLCEDPDNSLVFVGYQAEGSLGRRIQKGWKE
IPLKDEDDKMRVYNVRMNIKTIEGFSGHSDRRQLMEYVKRISPKPEKILL
CHGDNYKTLDLASSIYRTYRIETKTPLNLETVRIQ
Ligand information
Ligand IDZN
InChIInChI=1S/Zn/q+2
InChIKeyPTFCDOFLOPIGGS-UHFFFAOYSA-N
SMILES
SoftwareSMILES
CACTVS 3.341[Zn++]
ACDLabs 10.04
OpenEye OEToolkits 1.5.0		[Zn+2]
FormulaZn
NameZINC ION
ChEMBLCHEMBL1236970
DrugBankDB14532
ZINC
PDB chain2ycb Chain B Residue 1638 [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

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PDB2ycb Structure and Activity of a Novel Archaeal Beta-Casp Protein with N-Terminal Kh Domains.
Resolution3.1 Å
Binding residue
(original residue number in PDB)		H242 H244 H329 D352
Binding residue
(residue number reindexed from 1)		H241 H243 H328 D351
Annotation score4
Enzymatic activity
Enzyme Commision number 3.1.-.-
Gene Ontology
Molecular Function
GO:0003676 nucleic acid binding
GO:0003677 DNA binding
GO:0003723 RNA binding
GO:0004519 endonuclease activity
GO:0004521 RNA endonuclease activity
GO:0004527 exonuclease activity
GO:0004540 RNA nuclease activity
GO:0008270 zinc ion binding
GO:0042802 identical protein binding
GO:0046872 metal ion binding
Biological Process
GO:0006353 DNA-templated transcription termination

View graph for
Molecular Function
View graph for
Biological Process
External links
PDB RCSB:2ycb, PDBe:2ycb, PDBj:2ycb
PDBsum2ycb
PubMed21565697
UniProtO27271|FTTA_METTH Transcription termination factor FttA (Gene Name=fttA)

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