Structure of PDB 2x77 Chain B Binding Site BS02

Receptor Information

>2x77 Chain B (length=166) Species: 5664 (Leishmania major) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]

AWLASLKQTLGLLPADRKIRVLMLGLDNAGKTSILYRLHLGDVVTTNLET
LQYKNISFEVWDLGGCYFSDTDAVIYVVDSTDRDRMGVAKHELYALLDED
ELRKSLLLIFANKQDLPDAASEAEIAEQLGVSSIMNRTWTIVKSSSKTGD
GLVEGMDWLVERLREQ

Ligand information

Ligand ID

InChI

InChI=1S/Mg/q+2

InChIKey

JLVVSXFLKOJNIY-UHFFFAOYSA-N

SMILES

Software	SMILES
ACDLabs 10.04 OpenEye OEToolkits 1.5.0	[Mg+2]
CACTVS 3.341	[Mg++]

Formula

Name

MAGNESIUM ION

PDB chain

2x77 Chain B Residue 189 [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]

Receptor-Ligand Complex Structure

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PDB	2x77 Crystal Structure of Leishmania Major Adp Ribosylation Factor-Like 1 and a Classification of Related Gtpase Family Members in This Kinetoplastid.
Resolution	2.1 Å
Binding residue (original residue number in PDB)	T34 E57
Binding residue (residue number reindexed from 1)	T32 E49
Annotation score	1

Enzymatic activity

Enzyme Commision number

Gene Ontology

	Molecular Function
GO:0003924	GTPase activity
GO:0005525	GTP binding
GO:0046872	metal ion binding

	Biological Process
GO:0006622	protein targeting to lysosome
GO:0006886	intracellular protein transport
GO:0016192	vesicle-mediated transport
GO:0030100	regulation of endocytosis

	Cellular Component
GO:0005737	cytoplasm
GO:0005794	Golgi apparatus
GO:0005802	trans-Golgi network
GO:0031981	nuclear lumen
GO:0097014	ciliary plasm

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Cellular Component

External links

PDB	RCSB:2x77, PDBe:2x77, PDBj:2x77
PDBsum	2x77
PubMed	20801163
UniProt	Q4QEJ1

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