Structure of PDB 2wwy Chain B Binding Site BS02

Receptor Information
>2wwy Chain B (length=530) Species: 9606 (Homo sapiens) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
SPAAWNKEDFPWSGKVKDILQNVFKLEKFRPLQLETINVTMAGKEVFLVM
PTGGGKSLCYQLPALCSDGFTLVICPLISLMEDQLMVLKQLGISATMLNA
SSSKEHVKWVHAEMVNKNSELKLIYVTPEKIAKSKMFMSRLEKAYEARRF
TRIAVDEVHCCSQWGHDFRPDYKALGILKRQFPNASLIGLTATATNHVLT
DAQKILCIEKCFTFTASFNRPNLYYEVRQKPSNTEDFIEDIVKLINGRYK
GQSGIIYCFSQKDSEQVTVSLQNLGIHAGAYHANLEPEDKTTVHRKWSAN
EIQVVVATVAFGMGIDKPDVRFVIHHSMSKSMENYYQESGRAGRDDMKAD
CILYYGFGDIFRISSMVVMENVGQQKLYEMVSYCQNISKCRRVLMAQHFD
EVWNSEACNKMCDNCCKDSAFERKNITEYCRDLIKILKQAEELNEKLTPL
KLIDSWMGKGAAKLRVAGVVAPTLPREDLEKIIAHFLIQQYLKEDYSFTA
YATISYLKIGPKANLLNNEAHAITMQVTKS
Ligand information
Receptor-Ligand Complex Structure
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PDB2wwy Recq1 Helicase-Driven DNA Unwinding, Annealing, and Branch Migration: Insights from DNA Complex Structures
Resolution2.9 Å
Binding residue
(original residue number in PDB)		A563 Y564
Binding residue
(residue number reindexed from 1)		A500 Y501
Enzymatic activity
Enzyme Commision number 5.6.2.4: DNA 3'-5' helicase.
Gene Ontology
Molecular Function
GO:0003676 nucleic acid binding
GO:0004386 helicase activity
GO:0005524 ATP binding
Biological Process
GO:0006310 DNA recombination

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Molecular Function
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Biological Process
External links
PDB RCSB:2wwy, PDBe:2wwy, PDBj:2wwy
PDBsum2wwy
PubMed25831490
UniProtP46063|RECQ1_HUMAN ATP-dependent DNA helicase Q1 (Gene Name=RECQL)

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