Structure of PDB 2w35 Chain B Binding Site BS02

Receptor Information
>2w35 Chain B (length=223) Species: 2336 (Thermotoga maritima) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
MDYRQLHRWDLPPEEAIKVQNELRKKIKLTPYEGEPEYVAGVDLSFPGKE
EGLAVIVVLEYPSFKILEVVSERGEITFPYIPGLLAFREGPLFLKAWEKL
RTKPDVVVFDGQGLAHPRKLGIASHMGLFIEIPTIGVAKSRLYGTFKMPE
DKRCSWSYLYDGEEIIGCVIRTKEGSAPIFVSPGHLMDVESSKRLIKAFT
LPGRRIPEPTRLAHIYTQRLKKG
Ligand information
Receptor-Ligand Complex Structure
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PDB2w35 Structures of Endonuclease V with DNA Reveal Initiation of Deaminated Adenine Repair.
Resolution2.15 Å
Binding residue
(original residue number in PDB)		Y80 P82 G83 L85 D110 Q112 H116 I122 A138 K139 S140 R141 L142
Binding residue
(residue number reindexed from 1)		Y80 P82 G83 L85 D110 Q112 H116 I122 A138 K139 S140 R141 L142
Enzymatic activity
Enzyme Commision number 3.1.21.7: deoxyribonuclease V.
Gene Ontology
Molecular Function
GO:0000287 magnesium ion binding
GO:0003727 single-stranded RNA binding
GO:0004519 endonuclease activity
GO:0016891 RNA endonuclease activity, producing 5'-phosphomonoesters
GO:0043737 deoxyribonuclease V activity
GO:0046872 metal ion binding
Biological Process
GO:0006281 DNA repair
Cellular Component
GO:0005737 cytoplasm

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Biological Process
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Cellular Component
External links
PDB RCSB:2w35, PDBe:2w35, PDBj:2w35
PDBsum2w35
PubMed19136958
UniProtQ9X2H9|NFI_THEMA Endonuclease V (Gene Name=nfi)

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