Structure of PDB 2v6e Chain B Binding Site BS02

Receptor Information

>2v6e Chain B (length=531) Species: 255431 (Klebsiella phage phiKO2) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]

VKIGELINSLVSEVEAIDASDRPQGDKTKKIKAAALKYKNALFNDKRKFR
GKGLEKRISANTFNSYMSRARKRFDDRLHHNFEKNVIKLSEKYPLYSEEL
SSWLSMPAASIRQHMSRLQAKLKEIMPLAEDLSNIKIGTKNSEAKINKLA
NKYPEWQFAISDLNSEDWKDKRDYLYKLFQQGSSLLEDLNNLKVNHEVLY
HLQLSSAERTSIQQRWANVLSEKKRNVVVIDYPRYMQAIYDIINKPIVSF
DLTTRRGMAPLAFALAALSGRRMIEIMLQGEFSVAGKYTVTFLGQAKKRS
EDKGISRKIYTLCDATLFVSLVNELRSCPAAADFDEVIKGYGENDTRSEN
GRINAILATAFNPWVKTFLGDDRRVYKDSRAIYARIAYEMFFRVDPRWKN
VDEDVFFMEILGHDDENTQLHYKQFKLANFSRTWRPNVGEENARLAALQK
LDSMMPDFARGDAGVRIHETVKQLVEQDPSIKITNSTLRPFNFSTRLIPR
YLEFAADALGQFVGENGQWQLKDEAPAIVLP

Ligand information

>2v6e Chain E (length=25) [Search DNA sequence] [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]

cgcgcgtataatgggcaattgtgtg

Receptor-Ligand Complex Structure

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Structure summary

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PDB	2v6e An Interlocked Dimer of the Protelomerase Telk Distorts DNA Structure for the Formation of Hairpin Telomeres
Resolution	3.2 Å
Binding residue (original residue number in PDB)	N67 S71 R74 R212 Q216 W219 M276 I277 K300 R302 N357 A361 T362 N365 K369 V378 Y379 K380 K485 T487 N488 S489 R492 T498 R499 G520 Q521
Binding residue (residue number reindexed from 1)	N64 S68 R71 R209 Q213 W216 M273 I274 K297 R299 N354 A358 T359 N362 K366 V375 Y376 K377 K482 T484 N485 S486 R489 T495 R496 G517 Q518
Binding affinity	PDBbind-CN: Kd=17nM

Enzymatic activity

Enzyme Commision number

3.1.22.-

External links

PDB	RCSB:2v6e, PDBe:2v6e, PDBj:2v6e
PDBsum	2v6e
PubMed	17889664
UniProt	Q6UAV6\|PTELO_BPKO2 Protelomerase (Gene Name=26)

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