Structure of PDB 2rje Chain B Binding Site BS02

Receptor Information
>2rje Chain B (length=313) Species: 9606 (Homo sapiens) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
WSWESYLEEQKAITAPVSLFQDSQAVTHNKNGFKLGMKLEGIDPQHPSMY
FILTVAEVCGYRLRLHFDGYSECHDFWVNANSPDIHPAGWFEKTGHKLQP
PKGYKEEEFSWSQYLRSTRAQAAPKHLFVSQSHSPPPLGFQVGMKLEAVD
RMNPSLVCVASVTDVVDSRFLVHFDNWDDTYDYWCDPSSPYIHPVGWCQK
QGKPLTPPQDYPDPDNFCWEKYLEETGASAVPTWAFKVRPPHSFLVNMKL
EAVDRRNPALIRVASVEDVEDHRIKIHFDGWSHGYDFWIDADHPDIHPAG
WCSKTGHPLQPPL
Ligand information
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

[Spin on] [Spin off] [Reset]
[High quality] [Low quality]
[White background] [Black background]

[Spin on] [Spin off] [Reset]
[High quality] [Low quality]
[White background] [Black background]
PDB2rje L3MBTL1 recognition of mono- and dimethylated histones.
Resolution1.86 Å
Binding residue
(original residue number in PDB)
D355 M357 N358 F379 W382 Y386
Binding residue
(residue number reindexed from 1)
D150 M152 N153 F174 W177 Y181
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Biological Process
GO:0006355 regulation of DNA-templated transcription
Cellular Component
GO:0005634 nucleus

View graph for
Biological Process

View graph for
Cellular Component
External links
PDB RCSB:2rje, PDBe:2rje, PDBj:2rje
PDBsum2rje
PubMed18026117
UniProtQ9Y468|LMBL1_HUMAN Lethal(3)malignant brain tumor-like protein 1 (Gene Name=L3MBTL1)

[Back to BioLiP]