Structure of PDB 2rfm Chain B Binding Site BS02

Receptor Information
>2rfm Chain B (length=184) Species: 50339 (Thermoplasma volcanium) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
EIVEKIKDEKSINQNLDFLRNYRDSYNRTPLMVACMLGMENAIDKLVENF
DKLEDKDIEGSTALIWAVKNNRLGIAEKLLSKGSNVNTKDFSGKTPLMWS
IIFGYSEMSYFLLEHGANVNDRNLEGETPLIVASKYGRSEIVKKLLELGA
DISARDLTGLTAEASARIFGRQEVIKIFTEVRRA
Ligand information
Ligand IDBU2
InChIInChI=1S/C4H10O2/c1-4(6)2-3-5/h4-6H,2-3H2,1H3/t4-/m0/s1
InChIKeyPUPZLCDOIYMWBV-BYPYZUCNSA-N
SMILES
SoftwareSMILES
ACDLabs 10.04OCCC(O)C
OpenEye OEToolkits 1.5.0C[C@@H](CCO)O
CACTVS 3.341C[CH](O)CCO
CACTVS 3.341C[C@H](O)CCO
OpenEye OEToolkits 1.5.0CC(CCO)O
FormulaC4 H10 O2
Name1,3-BUTANEDIOL
ChEMBLCHEMBL1231501
DrugBankDB02202
ZINCZINC000001867144
PDB chain2rfm Chain B Residue 198 [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

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PDB2rfm Structural insights into an equilibrium folding intermediate of an archaeal ankyrin repeat protein
Resolution1.65 Å
Binding residue
(original residue number in PDB)		N26 Y27 R28 T34 K57
Binding residue
(residue number reindexed from 1)		N21 Y22 R23 T29 K52
Annotation score1
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Molecular Function
GO:0000976 transcription cis-regulatory region binding
Biological Process
GO:0045944 positive regulation of transcription by RNA polymerase II

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Molecular Function
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Biological Process
External links
PDB RCSB:2rfm, PDBe:2rfm, PDBj:2rfm
PDBsum2rfm
PubMed18305166
UniProtQ978J0|Y1425_THEVO Putative ankyrin repeat protein TV1425 (Gene Name=TV1425)

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