Structure of PDB 2q4h Chain B Binding Site BS02

Receptor Information
>2q4h Chain B (length=305) Species: 3702 (Arabidopsis thaliana) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
QSPELRKDPVTNRWVIFSPTDFKSSCPFCIGREQECAPELFRVPDHDPNW
KLRVIENLYPALSRNLETQSRTIVGFGFHDVVIESPVHSIQLSDIDPVGI
GDILIAYKKRINQIAQHDSINYIQVFKNQGASAGASMSHSHSQMMALPVV
PPTVSSRLDGTKDYFEETGKCCLCEAKSKHFVIDESSHFVSVAPFAATYP
FEIWIIPKDHSSHFHHLDDVKAVDLGGLLKLMLQKIAKQLNDPPYNYMIH
TSPLKVTESQLPYTHWFLQIVPQLSGVGGFEIGTGCYINPVFPEDVAKVM
REVSL
Ligand information
Ligand IDZN
InChIInChI=1S/Zn/q+2
InChIKeyPTFCDOFLOPIGGS-UHFFFAOYSA-N
SMILES
SoftwareSMILES
CACTVS 3.341[Zn++]
ACDLabs 10.04
OpenEye OEToolkits 1.5.0		[Zn+2]
FormulaZn
NameZINC ION
ChEMBLCHEMBL1236970
DrugBankDB14532
ZINC
PDB chain2q4h Chain B Residue 606 [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

[Spin on] [Spin off] [Reset]
[High quality] [Low quality]
[White background] [Black background]
[Spin on] [Spin off] [Reset]
[High quality] [Low quality]
[White background] [Black background]
PDB2q4h Ensemble refinement of protein crystal structures: validation and application.
Resolution1.834 Å
Binding residue
(original residue number in PDB)		C216 C219 H255
Binding residue
(residue number reindexed from 1)		C171 C174 H210
Annotation score1
Enzymatic activity
Catalytic site (original residue number in PDB) C63 C66 H133 N173 S181 H184 H186 Q188
Catalytic site (residue number reindexed from 1) C26 C29 H88 N128 S136 H139 H141 Q143
Enzyme Commision number 2.7.7.-
Gene Ontology
Molecular Function
GO:0008108 UDP-glucose:hexose-1-phosphate uridylyltransferase activity
GO:0008270 zinc ion binding
GO:0016779 nucleotidyltransferase activity
GO:0017103 UTP:galactose-1-phosphate uridylyltransferase activity
GO:0043531 ADP binding
GO:0046872 metal ion binding
GO:0047345 ribose-5-phosphate adenylyltransferase activity
Biological Process
GO:0005975 carbohydrate metabolic process
GO:0006006 glucose metabolic process
GO:0006012 galactose metabolic process
GO:0080040 positive regulation of cellular response to phosphate starvation

View graph for
Molecular Function
View graph for
Biological Process
External links
PDB RCSB:2q4h, PDBe:2q4h, PDBj:2q4h
PDBsum2q4h
PubMed17850744
UniProtQ9FK51|AGLUP_ARATH ADP-glucose phosphorylase (Gene Name=At5g18200)

[Back to BioLiP]