Structure of PDB 2oh2 Chain B Binding Site BS02

Receptor Information
>2oh2 Chain B (length=440) Species: 9606 (Homo sapiens) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
LNDNKAGMEGLDKEKINKIIMEATKGSRFYGNELKKEKQVNQRIENMMQQ
KAQITSQQLRKAQLQVDRFAMELEQSRNLSNTIVHIDMDAFYAAVEMRDN
PELKDKPIAVGSMSMLSTSNYHARRFGVRAAMPGFIAKRLCPQLIIVPPN
FDKYRAVSKEVKEILADYDPNFMAMSLDEAYLNITKHLEERQNWPEDKRR
YFIKNSVVFGTSAQEVVKEIRFRIEQKTTLTASAGIAPNTMLAKVCSDKN
KPNGQYQILPNRQAVMDFIKDLPIRKVSGIGKVTEKMLKALGIITCTELY
QQRALLSLLFSETSWHYFLHISLGLGSTHLTRDGERKSMSVERTFSEINK
AEEQYSLCQELCSELAQDLQKERLKGRTVTIKLKNVNFEVKTRASTVSSV
VSTAEEIFAIAKELLKTEIDADFPHPLRLRLMGVRISSFP
Ligand information
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

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PDB2oh2 Ternary complex of the catalytic core of human DNA polymerase Kappa with DNA and dTT
Resolution3.05 Å
Binding residue
(original residue number in PDB)		T44 F49 S134 M135 P153 I156 S388 T390 R413 K414 S415 M416 S417 V418 E419 R420 T421 R507
Binding residue
(residue number reindexed from 1)		T24 F29 S114 M115 P133 I136 S311 T313 R336 K337 S338 M339 S340 V341 E342 R343 T344 R430
Enzymatic activity
Enzyme Commision number 2.7.7.7: DNA-directed DNA polymerase.
Gene Ontology
Molecular Function
GO:0003684 damaged DNA binding
GO:0003887 DNA-directed DNA polymerase activity
Biological Process
GO:0006281 DNA repair

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Molecular Function
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Biological Process
External links
PDB RCSB:2oh2, PDBe:2oh2, PDBj:2oh2
PDBsum2oh2
PubMed
UniProtQ9UBT6|POLK_HUMAN DNA polymerase kappa (Gene Name=POLK)

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