Structure of PDB 2nuf Chain B Binding Site BS02

Receptor Information
>2nuf Chain B (length=219) Species: 63363 (Aquifex aeolicus) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
KMLEQLEKKLGYTFKDKSLLEKALTHVSYSKKEHYETLEFLGDALVNFFI
VDLLVQYSPNKREGFLSPLKAYLISEEFFNLLAQKLELHKFIRIKRGKIN
ETIIGDVFEALWAAVYIDSGRDANFTRELFYKLFKEDILSAIKEGRVKKD
YKTILQEITQKRWKERPEYRLISVEGPHHKKKFIVEAKIKEYRTLGEGKS
KKEAEQRAAEELIKLLEES
Ligand information
>2nuf Chain D (length=28) [Search RNA sequence] [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
caaggucauucgcaagaguggccuugcg
<<<<<<<<<<<....>>>>>>>>>>>..
Receptor-Ligand Complex Structure
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PDB2nuf A stepwise model for double-stranded RNA processing by ribonuclease III.
Resolution2.5 Å
Binding residue
(original residue number in PDB)		H27 V28 R97 N101 H179 H180 F184 K200 K202
Binding residue
(residue number reindexed from 1)		H26 V27 R96 N100 H178 H179 F183 K199 K201
Enzymatic activity
Enzyme Commision number 3.1.26.3: ribonuclease III.
Gene Ontology
Molecular Function
GO:0003723 RNA binding
GO:0003725 double-stranded RNA binding
GO:0004519 endonuclease activity
GO:0004525 ribonuclease III activity
GO:0042802 identical protein binding
GO:0046872 metal ion binding
Biological Process
GO:0006364 rRNA processing
GO:0006396 RNA processing
GO:0006397 mRNA processing
GO:0008033 tRNA processing
GO:0010468 regulation of gene expression
Cellular Component
GO:0005737 cytoplasm

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Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:2nuf, PDBe:2nuf, PDBj:2nuf
PDBsum2nuf
PubMed18047582
UniProtO67082|RNC_AQUAE Ribonuclease 3 (Gene Name=rnc)

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