Structure of PDB 2igi Chain B Binding Site BS02

Receptor Information
>2igi Chain B (length=179) Species: 83333 (Escherichia coli K-12) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
ANENNLIWIDLEMTGLDPERDRIIEIATLVTDANLNILAEGPTIAVHQSD
EQLALMDDWNVRTHTASGLVERVKASTMGDREAELATLEFLKQWVPAGKS
PICGNSIGQDRRFLFKYMPELEAYFHYRYLDVSTLKELARRWKPEILDGF
TKQGTHQAMDDIRESVAELAYYREHFIKL
Ligand information
Ligand IDZN
InChIInChI=1S/Zn/q+2
InChIKeyPTFCDOFLOPIGGS-UHFFFAOYSA-N
SMILES
SoftwareSMILES
CACTVS 3.341[Zn++]
ACDLabs 10.04
OpenEye OEToolkits 1.5.0		[Zn+2]
FormulaZn
NameZINC ION
ChEMBLCHEMBL1236970
DrugBankDB14532
ZINC
PDB chain2igi Chain B Residue 1010 [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

[Spin on] [Spin off] [Reset]
[High quality] [Low quality]
[White background] [Black background]
[Spin on] [Spin off] [Reset]
[High quality] [Low quality]
[White background] [Black background]
PDB2igi Crystal Structure of Oligoribonuclease, the lone essential exoribonuclease in Escherichia coli
Resolution1.7 Å
Binding residue
(original residue number in PDB)		E13 H157
Binding residue
(residue number reindexed from 1)		E12 H156
Annotation score4
Enzymatic activity
Enzyme Commision number 3.1.15.-
Gene Ontology
Molecular Function
GO:0000175 3'-5'-RNA exonuclease activity
GO:0003676 nucleic acid binding
GO:0004527 exonuclease activity
GO:0008310 single-stranded DNA 3'-5' DNA exonuclease activity
GO:0016896 RNA exonuclease activity, producing 5'-phosphomonoesters
GO:0034611 oligoribonucleotidase activity
GO:0046872 metal ion binding
Biological Process
GO:0006259 DNA metabolic process
GO:0006401 RNA catabolic process
Cellular Component
GO:0005737 cytoplasm
GO:0005829 cytosol

View graph for
Molecular Function
View graph for
Biological Process
View graph for
Cellular Component
External links
PDB RCSB:2igi, PDBe:2igi, PDBj:2igi
PDBsum2igi
PubMed
UniProtP0A784|ORN_ECOLI Oligoribonuclease (Gene Name=orn)

[Back to BioLiP]