Structure of PDB 2hih Chain B Binding Site BS02

Receptor Information
>2hih Chain B (length=386) Species: 1284 (Staphylococcus hyicus) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
AVQNPENPKNKDPFVFVHGFTGFVGEVAAKGENYWGGTKANLRNHLRKAG
YETYEASVSALASNHERAVELYYYLKGGRVDYGAAHSEKYGHERYGKTYE
GVLKDWKPGHPVHFIGHSMGGQTIRLLEHYLRFGDKAEIAYQQQHGGIIS
ELFKGGQDNMVTSITTIATPHNGTHASDDIGNTPTIRNILYSFAQMSSHL
GTIDFGMDHWGFKRKDGESLTDYNKRIAESKIWDSEDTGLYDLTREGAEK
INQKTELNPNIYYKTYTGVATHETQLGKHIADLGMEFTKILTGNYIGSVD
DILWRPNDGLVSEISSQHPSDEKNISVDENSELHKGTWQVMPTMKGWDHS
DFIGNDALDTKHSAIELTNFYHSISDYLMRIEKAES
Ligand information
Ligand IDCA
InChIInChI=1S/Ca/q+2
InChIKeyBHPQYMZQTOCNFJ-UHFFFAOYSA-N
SMILES
SoftwareSMILES
CACTVS 3.341[Ca++]
ACDLabs 10.04
OpenEye OEToolkits 1.5.0		[Ca+2]
FormulaCa
NameCALCIUM ION
ChEMBL
DrugBankDB14577
ZINC
PDB chain2hih Chain B Residue 1603 [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

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PDB2hih Structural basis of phospholipase activity of Staphylococcus hyicus lipase.
Resolution2.86 Å
Binding residue
(original residue number in PDB)		G290 D354 D357 D362 D365
Binding residue
(residue number reindexed from 1)		G284 D348 D351 D356 D359
Annotation score1
Enzymatic activity
Enzyme Commision number 3.1.1.3: triacylglycerol lipase.
3.1.1.32: phospholipase A1.
External links
PDB RCSB:2hih, PDBe:2hih, PDBj:2hih
PDBsum2hih
PubMed17582438
UniProtP04635|LIP_STAHY Lipase (Gene Name=lip)

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