Structure of PDB 2h0d Chain B Binding Site BS02

Receptor Information
>2h0d Chain B (length=100) Species: 9606 (Homo sapiens) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
KTWELSLYELQRTPQEAITDGLEIVVSPRSLHSELMCPICLDMLKNTMTT
KECLHRFCADCIITALRSGNKECPTCRKKLVSKRSLRPDPNFDALISKIY
Ligand information
Ligand IDZN
InChIInChI=1S/Zn/q+2
InChIKeyPTFCDOFLOPIGGS-UHFFFAOYSA-N
SMILES
SoftwareSMILES
CACTVS 3.341[Zn++]
ACDLabs 10.04
OpenEye OEToolkits 1.5.0		[Zn+2]
FormulaZn
NameZINC ION
ChEMBLCHEMBL1236970
DrugBankDB14532
ZINC
PDB chain2h0d Chain B Residue 204 [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
Receptor-Ligand Complex Structure
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PDB2h0d Structure of a Bmi-1-Ring1B Polycomb Group Ubiquitin Ligase Complex.
Resolution2.5 Å
Binding residue
(original residue number in PDB)		C67 H69 C87 C90
Binding residue
(residue number reindexed from 1)		C53 H55 C73 C76
Annotation score4
Enzymatic activity
Enzyme Commision number 2.3.2.27: RING-type E3 ubiquitin transferase.
Gene Ontology
Cellular Component
GO:0000151 ubiquitin ligase complex

View graph for
Cellular Component
External links
PDB RCSB:2h0d, PDBe:2h0d, PDBj:2h0d
PDBsum2h0d
PubMed16714294
UniProtQ99496|RING2_HUMAN E3 ubiquitin-protein ligase RING2 (Gene Name=RNF2)

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