Structure of PDB 2fcv Chain B Binding Site BS02

Receptor Information
>2fcv Chain B (length=299) Species: 317 (Pseudomonas syringae) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
KFALTAEQRASFEKNGFIGPFDAYSPEEMKETWKRTRLRLLDRSAAAYQD
NIANYDRHLDDDFLASHICRPEICDRVESILGPNVLCWRTEFFPKYPGDE
GTDWHQADTFANASGKPQIIWPENEEFGGTITVWTAFTDANIANGCLQFI
PGTQNSMNYDETKRMTYEPDANNSVVKDGVRRGFFGYDYRQLQIDENWKP
DEASAVPMQMKAGQFIIFWSTLMHASYPHSGESQEMRMGFASRYVPSFVH
VYPDSDHIEEYGGRISLEKYGAVQVIGDETPEYNRLVTHTTRGKKFEAV
Ligand information
Ligand IDAKG
InChIInChI=1S/C5H6O5/c6-3(5(9)10)1-2-4(7)8/h1-2H2,(H,7,8)(H,9,10)
InChIKeyKPGXRSRHYNQIFN-UHFFFAOYSA-N
SMILES
SoftwareSMILES
ACDLabs 10.04O=C(O)C(=O)CCC(=O)O
OpenEye OEToolkits 1.7.6C(CC(=O)O)C(=O)C(=O)O
CACTVS 3.385OC(=O)CCC(=O)C(O)=O
FormulaC5 H6 O5
Name2-OXOGLUTARIC ACID
ChEMBLCHEMBL1686
DrugBankDB08845
ZINCZINC000001532519
PDB chain2fcv Chain B Residue 898 [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

[Spin on] [Spin off] [Reset]
[High quality] [Low quality]
[White background] [Black background]
[Spin on] [Spin off] [Reset]
[High quality] [Low quality]
[White background] [Black background]
PDB2fcv Crystal structure of the non-haem iron halogenase SyrB2 in syringomycin biosynthesis.
Resolution1.8 Å
Binding residue
(original residue number in PDB)		F104 T113 H116 W145 L158 H235 R248 R254
Binding residue
(residue number reindexed from 1)		F93 T102 H105 W134 L147 H224 R237 R243
Annotation score5
Enzymatic activity
Enzyme Commision number 1.14.20.15: L-threonyl-[L-threonyl-carrier protein] 4-chlorinase.
Gene Ontology
Molecular Function
GO:0016491 oxidoreductase activity
GO:0046872 metal ion binding

View graph for
Molecular Function
External links
PDB RCSB:2fcv, PDBe:2fcv, PDBj:2fcv
PDBsum2fcv
PubMed16541079
UniProtQ9RBY6|SYRB2_PSESY L-threonyl-[L-threonyl-carrier protein] 4-chlorinase (Gene Name=syrB2)

[Back to BioLiP]