Structure of PDB 2f9p Chain B Binding Site BS02
Receptor Information
>2f9p Chain B (length=243) Species:
9606
(Homo sapiens) [
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IVGGQEAPRSKWPWQVSLRVRDRYWMHFCGGSLIHPQWVLTAAHCVGPDV
KDLATLRVQLREQHLYYQDQLLPVSRIIVHPQFYIIQTGADIALLELEEP
VNISSRVHTVMLPPASETFPPGMPCWVTGWGDVDNDEPLPPPFPLKQVKV
PIMENHICDAKYHLGAYTGDDVRIIRDDMLCAGNSQRDSCKGDSGGPLVC
KVNGTWLQAGVVSWGEGCAQPNRPGIYTRVTYYLDWIHHYVPK
Ligand information
>2f9p Chain G (length=3) Species:
66430
(Streptomyces roseus) [
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LLR
Receptor-Ligand Complex Structure
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PDB
2f9p
X-ray Structures of Free and Leupeptin-complexed Human alpha I-Tryptase Mutants: Indication for an alpha to beta-Tryptase Transition
Resolution
2.3 Å
Binding residue
(original residue number in PDB)
I96 I97
Binding residue
(residue number reindexed from 1)
I85 I86
Enzymatic activity
Enzyme Commision number
3.4.21.59
: tryptase.
Gene Ontology
Molecular Function
GO:0004252
serine-type endopeptidase activity
GO:0005515
protein binding
GO:0008236
serine-type peptidase activity
GO:0042802
identical protein binding
Biological Process
GO:0006508
proteolysis
GO:0006952
defense response
GO:0022617
extracellular matrix disassembly
Cellular Component
GO:0005576
extracellular region
GO:0005615
extracellular space
GO:0062023
collagen-containing extracellular matrix
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Molecular Function
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Biological Process
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Cellular Component
External links
PDB
RCSB:2f9p
,
PDBe:2f9p
,
PDBj:2f9p
PDBsum
2f9p
PubMed
16414069
UniProt
Q15661
|TRYB1_HUMAN Tryptase alpha/beta-1 (Gene Name=TPSAB1)
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