Structure of PDB 2ev5 Chain B Binding Site BS02

Receptor Information

>2ev5 Chain B (length=131) Species: 1423 (Bacillus subtilis)

PSMEDYIEQIYMLIEEKGYARVSDIAEALAVHPSSVTKMVQKLDKDEYLI
YGLVLTSKGKKIGKRLVYRHELLEQFLRIIGVDEEKIYNDVEGIEHHLSW
NSIDRIGDLVQYFEEDDARKKDLKSIQKKTE

Ligand information

• Ligand ID: CA
• InChI: InChI=1S/Ca/q+2
• InChIKey: BHPQYMZQTOCNFJ-UHFFFAOYSA-N
• SMILES:
  CACTVS 3.341: [Ca++]
  ACDLabs 10.04
  OpenEye OEToolkits 1.5.0: [Ca+2]
• Formula: Ca
• Name: CALCIUM ION
• DrugBank: DB14577
• PDB chain: 2ev5 Chain B Residue 2151

Receptor-Ligand Complex Structure

Structure summary

• PDB: 2ev5 Structural Basis for the Metal-Selective Activation of the Manganese Transport Regulator of Bacillus subtilis.
• Resolution: 2.0 Å
• Binding residue (original residue number in PDB): D8 E99 E102 H103
• Binding residue (residue number reindexed from 1): D5 E92 E95 H96
• Annotation score: 4

Gene Ontology

Molecular Function

• GO:0003677 DNA binding
• GO:0003700 DNA-binding transcription factor activity
• GO:0030145 manganese ion binding
• GO:0046872 metal ion binding
• GO:0046914 transition metal ion binding
• GO:0046983 protein dimerization activity

Biological Process

• GO:0006355 regulation of DNA-templated transcription
• GO:0030026 intracellular manganese ion homeostasis

Cellular Component

• GO:0005737 cytoplasm

External links

• PDB: RCSB:2ev5, PDBe:2ev5, PDBj:2ev5
• PDBsum: 2ev5
• PubMed: 16533030
• UniProt: P54512|MNTR_BACSU HTH-type transcriptional regulator MntR (Gene Name=mntR)